Sveinsson's chorioretinal atrophy

(redirected from HPCD)
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Sveinsson's chorioretinal atrophy

An extremely rare autosomal dominant (OMIM:108985) that primarily affects Icelandics, with most cases tracing back to a male founder born in 1540, characterised by symmetrical lesions radiating from the optic disk involving the retina and the choroid.

Molecular pathology
Defects of TEAD1, which encodes a ubiquitous transcription enhancer of the TEA/ATTS domain family, cause Sveinsson's chorioretinal atrophy.
References in periodicals archive ?
Beat-by-beat HPCD hemodynamic evaluation method that was combination of Gregg's HPCD method and our beat-by-beat cardiovascular measurement was proposed and attempted.
No evidence exists to support the Company's claims that Mitoyztrex is superior to the existing formulations of mitomycin; (c) That there is no existing evidence that the addition of HPCD yields any clinical advantage over the original formulation of mitomycin; (d) That SuperGen's "Extra" technology did not shield the drug at the injection site; and (e) That the so-called "advantages" of the Company's product, including increased solubility, stability and shelf-life, were non-existent.
Chief Rhodes is currently leading the HPCD through the process of becoming an accredited law enforcement agency in South Carolina.