CES1

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CES1

A gene on chromosome 16q22.2 that encodes a member of the carboxylesterase family, which hydrolyse or transesterify xenobiotics (e.g., cocaine and heroin) and endogenous substrates with ester,
thioester or amide bonds. CES1 may participate in fatty acyl and cholesterol ester metabolism, and may play a role in maintaining the blood-brain barrier. It is the major liver enzyme and functions in liver drug clearance.
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In the present study PACE did not have any correlation with HMSE or IADL score, suggesting that the severity of dementia did not influence PACE significantly.
In addition, comparing the loss functions about the SV and SV-RV models, the loss functions of SV model are smaller than those of the SV-RV model apart from the HMSE value.
MAE HMAE MSE HMSE QLIKE [R.sup.2]LOG SV 2.3879 0.7237 1.0140 34.830 2.2034 0.4572 SV-RV 2.3197 0.7104 0.9862 32.099 2.1941# 0.4377 SV-CJ 2.2951# 0.6736# 0.8440# 31.167# 2.1983 0.4203# The bold part is the minimum value of each loss function.