HMPAO


Also found in: Acronyms.

HMPAO

technetium-99m

99mTc.
A radioactive isotope of technetium having a half-life of 6 hr, in which the “m” refers to the fact that it is a metastable isotope.. 99mTc is used in nuclear medicine for a wide variety of diagnostic tests and imaging studies, e.g., myocardial perfusion scans, bone scans, and V/Q scans..

technetium Tc 99m albumin aggregated injection

An injection of technetium-99m that has been aggregated with albumin. It is used intravenously to scan the lungs.

technetium Tc 99m hexamethylpropyleneamine oxime

Abbreviation: HMPAO
A radioactive tracer consisting of technetium-99m linked to hexamethylpropyleneamine oxime. It is used to make nuclear imaging scans of the brain, e.g., in the determination of brain death. Absence of uptake of the molecule by the brain is diagnostic of brain death.

technetium 99m (methoxyisonitrile) MIBI

A radioactive tracer consisting of technetium-99m linked to MIBI. It is used in nuclear medical imaging (e.g., in scintimammography) to identify cancerous breast masses. Other uses of technetium 99m MIBI include cardiac, parathyroid, and thyroid imaging.

technetium Tc 99m methylene diphosphonate

A radioactive tracer consisting of technetium-99m linked to methylene diphosphonate. It is used in nuclear medicine to obtain images of bone and bone diseases, e.g., fractures not seen on plain x-rays, malignancies, and osteomyelitis.

technetium Tc 99m RBC

A radioactive tracer consisting of technetium-99m linked to red blood cells. It is used in clinical medicine to evaluate occult bleeding, e.g., from the gastrointestinal tract, or the motion of the heart in gated blood pool imaging.
Synonym: red blood cell scan

technetium Tc 99m sestamibi

A radioactive tracer consisting of technetium-99m linked to sestamibi. It is used to image blood flow to the heart muscle, esp. when combined with exercise or pharmacological “stress” tests. In a heart with normal blood flow, the isotope should be taken up uniformly throughout the heart muscle. Decreased uptake by regions of the heart occurs when coronary artery blood flow to those regions is blocked, e.g., by atherosclerotic plaque. Synonym: sestamibi

technetium Tc 99m sulfur colloid

A radioactive tracer consisting of technetium-99m linked to sulfur colloid. It is used in nuclear medicine scans to make images of gastric emptying or of the lymph nodes, liver, and spleen.

technetium Tc 99m hexamethylpropyleneamine oxime

Abbreviation: HMPAO
A radioactive tracer consisting of technetium-99m linked to hexamethylpropyleneamine oxime. It is used to make nuclear imaging scans of the brain, e.g., in the determination of brain death. Absence of uptake of the molecule by the brain is diagnostic of brain death.
See also: technetium-99m
References in periodicals archive ?
Protocol for SPECT using Tc-99m HMPAO based on guidelines given in the manual of socity of nuclear medicine11.
CONCLUSION This study found significantly decreased overall cerebral perfusion in chronic tobacco users when compared with the non-tobacco users, through semi-quantitative scintigraphic assessment employing Tc-99m HMPAO SPECT.
Evaluation of cerebral blood flow in patients with idiopathic orthostatic hypotension using Tc-99m HMPAO brain SPECT during postural testing.
The use of Technetium 99m with HMPAO in the mid-1980s led to other studies of brain function including patients with stroke, arteriovenous malformation (AVM), transient ischemic attacks (TIAs), hemorrhage, dementia and seizures.
In 1994, since HMPAO could not be mixed in advance, the procedure we performed when a patient had a seizure was as follows:
Differences in HMPAO uptake were analyzed using SPM8 software (Wellcome Department of Cognitive Neurology, London, UK) implemented on the Matlab platform (MathWorks Inc.
21] Technetium Tc 99m HMPAO scintigraphy of the axial skeleton can yield a "cold"-defect imaging pattern, failing to mark infection and bone damage "hot spots.
Although it is not clear why, SPECT studies show that HSE significantly increases Tc 99m HMPAO uptake 4 to 13 days after initial symptoms.
HMPAO SPECT to assess neurologic deficits during balloon test occlusion.
The agents commonly employed in epilepsy imaging are Tc 99m HMPAO (hexamethylpropyline amine oxime) and TC 99m ECD (ethyl cysteinate dimer).
10) Bleeding and inflammatory reaction with necrosis was noted in the accumulation of Tc-99m HMPAO in malignant abdominal tumors.
This article has briefly covered the following uses: GI bleeding scintigraphy with Tc-99m RBCs, appendicitis imaging with Tc-99m HMPAO WBCs, and cholescintigraphy with Tc-99m MAG3 for acute urinary obstruction.