HMPAO


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HMPAO

Farlex Partner Medical Dictionary © Farlex 2012

technetium-99m

99mTc.
A radioactive isotope of technetium having a half-life of 6 hr, in which the “m” refers to the fact that it is a metastable isotope.. 99mTc is used in nuclear medicine for a wide variety of diagnostic tests and imaging studies, e.g., myocardial perfusion scans, bone scans, and V/Q scans..

technetium Tc 99m albumin aggregated injection

An injection of technetium-99m that has been aggregated with albumin. It is used intravenously to scan the lungs.

technetium Tc 99m hexamethylpropyleneamine oxime

Abbreviation: HMPAO
A radioactive tracer consisting of technetium-99m linked to hexamethylpropyleneamine oxime. It is used to make nuclear imaging scans of the brain, e.g., in the determination of brain death. Absence of uptake of the molecule by the brain is diagnostic of brain death.

technetium 99m (methoxyisonitrile) MIBI

A radioactive tracer consisting of technetium-99m linked to MIBI. It is used in nuclear medical imaging (e.g., in scintimammography) to identify cancerous breast masses. Other uses of technetium 99m MIBI include cardiac, parathyroid, and thyroid imaging.

technetium Tc 99m methylene diphosphonate

A radioactive tracer consisting of technetium-99m linked to methylene diphosphonate. It is used in nuclear medicine to obtain images of bone and bone diseases, e.g., fractures not seen on plain x-rays, malignancies, and osteomyelitis.

technetium Tc 99m RBC

A radioactive tracer consisting of technetium-99m linked to red blood cells. It is used in clinical medicine to evaluate occult bleeding, e.g., from the gastrointestinal tract, or the motion of the heart in gated blood pool imaging.
Synonym: red blood cell scan

technetium Tc 99m sestamibi

A radioactive tracer consisting of technetium-99m linked to sestamibi. It is used to image blood flow to the heart muscle, esp. when combined with exercise or pharmacological “stress” tests. In a heart with normal blood flow, the isotope should be taken up uniformly throughout the heart muscle. Decreased uptake by regions of the heart occurs when coronary artery blood flow to those regions is blocked, e.g., by atherosclerotic plaque. Synonym: sestamibi

technetium Tc 99m sulfur colloid

A radioactive tracer consisting of technetium-99m linked to sulfur colloid. It is used in nuclear medicine scans to make images of gastric emptying or of the lymph nodes, liver, and spleen.

technetium Tc 99m hexamethylpropyleneamine oxime

Abbreviation: HMPAO
A radioactive tracer consisting of technetium-99m linked to hexamethylpropyleneamine oxime. It is used to make nuclear imaging scans of the brain, e.g., in the determination of brain death. Absence of uptake of the molecule by the brain is diagnostic of brain death.
See also: technetium-99m
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Radiopharmaceutical preparation of HMPAO is relatively straightforward, and the technetium gamma emitter is widely available in clinical practice [58].
This study was done to determine an association between chronic tobacco use and changes in cerebral perfusion (hypoperfusion or hyperperfusion), through semi-quantitative scintigraphic assessment employing Tc-99m HMPAO SPECT PATIENTS AND METHODS The research project was conducted at the Department of Medical Sciences, P.I.E.A.S.
Brain single-photon emission tomography with 99mTc HMPAO in neuropsychiatric systemic lupus erythematosus: Relations with EEG and MRI findings and clinical manifestations.
There are many studies that underline the usefulness of HMPAO labeled leukocyte SPECT imaging to assess for active cranial osteomyelitis after treatment and follow-up of this patients.
The use of Technetium 99m with HMPAO in the mid-1980s led to other studies of brain function including patients with stroke, arteriovenous malformation (AVM), transient ischemic attacks (TIAs), hemorrhage, dementia and seizures.[11] A group of neurologists in Melbourne, Australia were pioneers in the study of ictal, interictal and postictal SPECT and published several articles in journals years before HMPAO was approved by the FDA here in the United States.
Interactive three dimensional region of interest analysis of Tc-99m HMPAO SPECT brain images.
Tc-99m HMPAO veya In-111 oxine isaretli lokosit SPECT: Enfeksiyon bolgelerinde lokositlerin birikmesi esasina dayanan bu iki yontemden Tc-99m-HMPAO, In111-oxin'egoredahasikkullanilmaktadir.Bugoruntuleme yontemi enfeksiyon goruntuleme icin spesifiktir.
Futatsuya et al., "Basilar artery migraine: reversible ischemia demonstrated by Tc-99m HMPAO brain SPECT," Clinical Nuclear Medicine, vol.
[sup.111] In-oxine and [sup.99]mTc- hexamethylpropyleneamineoxime (HMPAO) were widely used for labeling white blood cells in preclinical and clinical studies, and these were also applied for tracking EVs [20, 21].
The imaging of cerebral metabolism indirectly via perfusion SPECT using Tc-99m hexamethylpropylene amine oxine (HMPAO) or ethylene cystinate dimer (ECD), or directly with PET using [F-18] fluorodeoxyglucose (FDG), is clinically well established.