HMB-45


Also found in: Wikipedia.

HMB-45

An antibody to a premelanosome glycoprotein found to be present in melanomas and other tumors derived from melanocytes.
Mentioned in ?
References in periodicals archive ?
Immunohistochemical staining revealed that the tumor cells were immunoreactive for vimentin, HMB-45, S-100, and Melan-A.
Radiological Findings of the Primary Female Urethral Malignant Melanoma: A Rare Case Report
Immunoreactivity for vimentin, S-100 protein, and HMB-45 is regularly present, melanocytomas in contradistinction to meningiomas--being EMA negative.
NEUROCUTANEOUS MELANOSIS
Immunocytochemical staining with thyroglobulin and TTF-1 combined with melanocytic markers, for example MARTI (melanoma antigen recognized by T cells 1), HMB-45 (human melanoma black 45) (Figure 3, D), S-100 protein, and microphthalmia transcription factor (MITF), can be useful in these cases.
Metastases to the Thyroid: Potential Cytologic Mimics of Primary Thyroid Neoplasms
Markers of muscular differentiation (desmin, myogenin, MyoD1, and smooth-muscle actin) and melanocytic markers (S100-protein, HMB-45, and melan-A) were negative.
Pseudomyogenic hemangioendothelioma: a little-known tumor
Neoplastic cells were positive for S100, HMB-45, and vimentin.
Congenital malignant melanoma of the dura
The histopathological diagnosis can be assisted by the use of immunohistochemical markers, such as HMB-45 and S-100.
PRIMARY MALIGNANT MELANOMA OF THE FEMALE URETHRA - A CASE REPORT/PRIMARNI MALIGNI MELANOM ZENSKE URETRE - PRIKAZ SLUCAJA
(New Jersey), using the following antibodies; S100, Human Melanoma Black 45 (HMB-45), vimentin, Melan A, factor XIIIa, and CD68.
Primary Clear Cell Sarcoma of the Dermis Mimicking Malignant Melanoma
Anti-human cytokeratin s-100, Ready to use; Melanoma, Hmb-45 clone, Ready for use; Monocl.
Delivery Of Reagents For Immunohistochemical Research For The Needs Of Kot-ruse Eood
Incisional biopsy of the left inguinal lymph node revealed metastatic round cell tumor which is immunohistochemistry positive for vimentin, S100, and HMB-45. The immunophenotype is consistent with malignant melanoma (Figure 1).
Metastatic Melanoma of Uncertain Primary with 5-Year Durable Response after Conventional Therapy: A Case Report with Literature Review
(d) HMB-45 demonstrates salient cytoplasmic immunoreactivity, supporting melanocytic phenotype (HMB-45, 400x).
An Inguinal Perivascular Epithelioid Cell Tumor Metastatic to the Orbit
The cells showed a positive reaction for HMB-45 antigen [Figure 1]b.
Pulmonary Lymphangiomyomatosis Associated with Renal and Hepatic Angiomyolipoma Mass in a Patient with Tuberous Sclerosis Complex
The patient was diagnosed with PEComa following human melanoma black-45 (HMB-45) monoclonal antibody expression and 2 mitoses under 50x magnification during pathological examination.
Perivascular Epithelioid Cell Tumor of the Kidney: A Rare Case Report / Bobregin Perivaskuler Epiteloid Hucre Tumoru: Nadir Bir Olgu Sunumu

Medical browser ?
Full browser ?