HLA-B


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HLA-B

abbreviation for human leukocyte antigen B. See human leukocyte antigen.
References in periodicals archive ?
15] In this study, we aimed to analyze HLAA, HLA-B, HLA-C, HLA-DRB1*, HLA-DRB3*, HLA-DRB4*, HLA-DRB5*, HLA-DQB1 loci expression in patients with RA in the Federation of Bosnia and Herzegovina.
Disease susceptibility has consistently been associated with many subtypes of HLA-B gene, particularly HLA-B51.
Samples (n = 2532) were tested with a commercial kit (Holotype, Omixon) for 8 or more loci (full length HLA-A, HLA-B, HLA-C, DPA1, DQA1, and DQB1; introns 1 to 4 of DRB1; and intron 1 to the 3' untranslated region of DPB1, the details of which were previously published (9)).
Major histocompatibility complex, class I, A (HLA-A) [5] and HLA-C both contain 8 exons, and HLA-B contains 7 exons.
In the donors' group was identified 15 alleles for the locus HLA-A, 25 alleles for the locus HLA-B and 14 for the locus HLA-DRB1 and in the recipients' group was identified 20, 34, and 15 different alleles for the locus HLA-A, -B and -DRB1, respectively.
The present study suggests that HLA-DQB1 typing, better than the HLA-B, may help on decisions regarding toxoplasmosis prophylaxis.
Allele Specific PCR RT-PCR HLA-B x 27 positive 139 139 HLA-B x 27 negative 302 302 RCPA QAP HLA-B x 27 positive 4 4 RCPA QAP HLA-B x 27 negative 8 * 8 * Total 453 453 * Four of the HLA-B*27 external quality assurance samples provided by the RCPA Immunology QAP program were reported as heterozygote for HLA-B*7.
15) stated that HLA-B alleles were served as the dominant MHC class I restricting molecules for anti-mycobacterium-specific CD8+ T cell responses measured in CD8+ T cells from patients with PT.
HLA-B low-resolution typing was performed using OLERUP-HLA-B (OLERUP SSP AB, Saltsjobaden, Sweden) typing kit (lot #91) according to the manufacturer's instructions.
De los tres locus del CMH-I, se ha demostrado que el HLA-B tiene un papel dominante en la respuesta de los LTC contra el VIH, comparado con los otros dos locus; estas diferencias se pueden explicar parcialmente por el mayor polimorfismo que exhibe este alelo en la poblacion, sumado al hecho de que las respuestas generadas son de mayor magnitud en comparacion con las que ocurren en el contexto de HLA- A y C (23).
Pediatric kidney transplant patients may benefit from change in HLA-B matching policy Avoiding mismatching cell surface antigens between donors and recipients might benefit pediatric kidney transplant patients, according to a new study in the July Archives of Surgery.