HLA typing

HLA typ·ing

tests done in order to determine if a patient has antibodies against a potential donor's HLA. The presence of antibodies means that a particular graft will be rapidly rejected; also used to establish paternity and in forensic medicine.

hu·man leu·ko·cyte an·ti·gen typ·ing

(hyūmăn lūkō-sīt anti-jen tīping)
Tests done to determine whether a patient has antibodies against a potential donor's HLAs. The presence of antibodies means that a graft will be rejected.
Synonym(s): HLA typing.
References in periodicals archive ?
Contract award notice: Supply of reagents, Consumables and interpretation software for hla typing by ngs technology on illumina platform (france-clermont-ferrand: Laboratory reagents)
*PCR-based molecular assay captured the largest share in the overall market in 2016 due to extensive adoption in HLA typing *The sequencing-based typing segment is anticipated to witness significant growth from 2016 to 2024.
For More Information on This Report, Please Visit @ https://www.mrrse.com/asia-preimplantation-genetic-diagnosis-market The information presented in this review is based on a MRRSE report, titled "Preimplantation Genetic Diagnosis Market (Test - PGD for Chromosomal Aberrations, Aneuploidy Screening, Gender Selection, Single Gene Disorder, HLA Typing, and X-linked Diseases) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2014 - 2020." The global PGD market has been segmented as presented below: Global PGD Market by Test
Pacific Biosciences announced that a retrospective study conducted by scientists at the Anthony Nolan Research Institute in the UK demonstrated that ultra-high-resolution HLA typing performed with PacBio sequencing identified stronger matches associated with improved survival rates among patients who received hematopoietic cell transplants.
Preimplantation Genetic Testing to find Largest Application in Embryo HLA Typing for Stem Cell Therapy Embryo HLA typing for stem cell therapy is expected to show healthy growth from throughout 2017-2022.
Advances in DNA sequencing have revolutionized many tests commonly used in or ordered by clinical laboratories, but the implications for HLA typing have been particularly impressive.
From the HLA Typing Research Unit (Zalzala, Mohammedsalih, Mahdi), College of Medicine, and from the Department of Medicine (Abdullah, Yaseen), Al-kindy College of Medicine, University of Baghdad, Baghdad, Iraq.
HLA typing by serology: During the last 40 years HLA typing to detect this polymorphism was undertaken by the serological method better known as the complement-dependent cytotoxicity assay (CDC).
In this optic, HLA typing emerges as an important tool able to discriminate individuals genetically susceptible to CD in at-risk groups such as those with autoimmune conditions (e.g., thyroiditis) (4).
Because of the lower throughput of the available technologies and to reduce the number of polymorphic sites to interrogate, early molecular strategies for clinical HLA typing focused on characterization of the antigen recognition site only (exons 2 and 3 for class I; exon 2 for class II).
Based on test type, the market is segmented into antibody screening, HLA typing, cross-matching tests, ABO blood tests, and antigen typing.
The comapny, through its recently acquired Olerup franchise, has a presence in the pre-transplant HLA typing market.