HLA mismatch

HLA mismatch

The nonmatching of HLA antigen in recipients of renal and other allografts. See Transplantation. Cf HLA match.

HLA mismatch

, human leukocyte antigen mismatch
The number of human leukocyte antigens (HLAs) found on the cells of a donor organ but not found on the cells of the organ recipient. The greater the disparity between the antigens, the lower the probability of a successful transplantation.
References in periodicals archive ?
HLA mismatch, donors who were hypertensive, recipients with diabetes).
Should HLA mismatch acceptability for sensitized transplant candidates be determined at the high-resolution rather than the antigen level?
Humoral/AMR rejection cases (C4d deposition in the peritubular capillaries) and the cellular rejection biopsies as per the BANFF 2003 criteria were correlated with their HLA mismatch scoring, pre-transplant PRA levels.
HLA mismatch '3' was found in 30 cases (60 percent).
Based on the HLA mismatch, cases were broadly classified into two groups.
Rest of the 20 cases (40 percent) were shown > 50% HLA mismatch.
Comparison of C4d positive cases with their HLA mismatch scoring status: Association between these two variables was statistically significant (Table 3).
The main objective of the three year project is to determine the clinical value of implementing a Europe-wide acceptable HLA mismatch program to facilitate more as well as safer transplantations on highly sensitized patients all over Europe.