HLA match

Immunology The number of HLA antigens at the HLA-A, B, and DR loci of donor and recipient that match, from a maximum of 6 to minimum of 0. Cf HLA mismatch.

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k)] can be derivate with respect to k donors in order to estimate the number of additional donors required to increase by 1% the expectative of finding a donor with complete or partial HLA match for a q recipient in the waiting list.

Compatibilidad HLA donante-receptor y probabilidades de trasplante renal en una poblacion colombiana

This technique allows couples to se in vitro fertilisation (IVF) with pre-implantation genetic diagnosis to identify embryos that are an HLA match and only use those embryos to establish pregnancy," he added.

Unborn test-tube baby to save thalassemic sibling

8) The embryo created would be a definite HLA match, and, upon birth, could begin to serve as a hematopoietic stem cell transplant ("HSCT") donor for a compatible person in need, such as a sick sibling.

Genetic material girl: embryonic screening, the donor child, and the need for statutory reform

This demonstrates the continued risk of allogeneic stem cell transplantation, as the patient in question was a 10 out of 10 HLA match, was on appropriate immunosuppressive therapies to prevent such a reaction and still developed significant GvHD complications in less than one month.

Atypical cytogenetics in therapy-related myelodysplastic syndrome secondary to indolent B-cell lymphoma

If the blood is an HLA match for the sick child, those cells could potentially be used in the child's treatment.

Life blood: hidden wealth in the human umbilical cord is offering new hope for patients with leukemia and fatal genetic blood disorders

Once we found an HLA match, we implanted the embryo into the mother's uterus.

Baby will help cure sibling with thalassaemia

Umbilical cord blood, the other alternative source of stem cells, is useful for children and for small adults (under 50 kg) and furthermore requires a less stringent HLA match.

The South African bone marrow registry (SABMR) and allogeneic bone marrow transplantation

And, there has always been a considerable chance that the recipient's body will reject the transplanted cells (graft-versus-host disease), even from siblings, who provide the best chance for perfect HLA match.

To bank or not to bank, that is the question

There is a 25% chance of a 6/6 haplo-identical HLA match for each sibling, which is the ideal situation for a transplant.

Umbilical cord blood: an overview

Multiple cycles of IVF and PGD are often needed to produce an HLA match.

Born to heal: screening embryos to treat siblings raises hopes, dilemmas

There are different methods for assuring a close HLA match, and they raise different issues.

Conception to obtain hematopoietic stem cells

Even though 66 patients received cordblood that was not a perfect HLA match, 20% of recipients in the cord blood group had severe acute GVHD.