borderline leprosy

(redirected from HLA B27)

bor·der·line lep·ro·sy

a form of leprosy that is very unstable immunologically; the cutaneous nerves frequently contain bacilli, but the lepromin test is usually negative; cutaneous lesions are composed of flat bands or plaques.
Synonym(s): dimorphous leprosy

borderline leprosy

A term for one of two presentations of leprosy, borderline tuberculous leprosy—in which there are a smattering of reactive granulomas with scattered large, sharply demarcated, hairless anaesthetic plaques—and borderline lepromatous leprosy—characterised by skin nodules filled with numerous bacilli.
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References in periodicals archive ?
The allele and genotype frequencies for the investigated SNPs in this Caucasian cohort were comparable to those reported for the European individuals in the 1000 genes project (Figure 1), with allele and genotype distribution independent of HLA B27 status (all p>0.2).
Tenders are invited for Hla b27 low resolution ssp kit
Spondyloarthropathy is genetically linked (90% of cases), and the strongest contributing factor is the HLA B27 antigen [1,2].
We are obliged to Rheumatologists and orthopaedic surgeons for sending us patients for HLA B27 testing.
Mcmichael, "Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27," International Immunology, vol.
It has a strong genetic predisposition with a high proportion of patients carrying the HLA B27 genotype [2].
Typically, the prevalence of AS in a population reflects the associated prevalence of HLA B27 gene in that population.1
Os criterios de exclusao sao a presenca de psoriase no paciente ou parente de primeiro grau; artrite em menino HLA B27 apos os seis anos; espondilite anquilosante (EA), ARE, sacroiliite (SII) em Doenca Inflamatoria Intestinal (DII), Artrite Reativa, uveite anterior aguda ou historia de alguma dessas desordens em parente de primeiro grau; e presenca de FR positivo em duas ocasioes com tres meses de diferenca.
Occult blood in stool, urinary microscopy, brucella, anti-HCV, rheumatoid factor, HLA B27, anti-nuclear antibody (ANA), anti-neutrophilic cytoplasmic antibody (ANCA), and extractable nuclear antigens panel were negative.
HLA B27 was positive in 100% of the patients and positive family history was present in 12 % of the patients.
Her HLA B27 was negative and she was treated with methotrexate.
Vaara et al., "Molecular mimickry between HLA B27 and Yersinia, Salmonella, Shigella and Klebsiella within the same region of HLA [alpha]1-helix," Clinical and Experimental Immunology, vol.