HIV nephropathy

(redirected from HIV associated nephropathy)
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HIV nephropathy

AIDS-associated nephropathy Renal disease linked to HIV infection–eg, focal or global glomerulosclerosis with mesangial deposition of C3, IgM, and occasionally IgG, and HIV-associated IgA nephropathy Clinical Severe nephrotic syndrome of abrupt onset, ↓ albumin, rapidly progressive ESRD. See End-stage renal disease.
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In 2% of cases, the cause was HIV associated nephropathy.
The single most common cause of CKD clinically was diabetes alone in 33% cases followed by hypertension alone in 17% cases, 5% cases had co-existing diabetes and hypertension combined and in 2% cases had HIV associated nephropathy.
Renal Data System (USRDS) (2008) reports that annually approximately 800 new patients starting dialysis between 2002 and 2006 cite HIV associated nephropathy (HIVAN) as the cause of their renal failure.
In six cases indication for biopsy was, active urine sediment with abrupt onset of proteinuria, the biopsy reports were turned out to be PIGN in two cases, MPGN type 1 in two cases, HIV associated nephropathy in one case, Membranous nephropathy in one case.
Preliminary studies suggest that discontinuation of Zidovudine in treatment of HIV associated nephropathy may cause an irreversible, rapid loss of renal function.