histone

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histone

 [his´tōn]
a simple protein, soluble in water and insoluble in dilute ammonia, found combined as salts with acidic substances, such as nucleic acids or the globin of hemoglobin.

his·tone (H),

(his'tōn),
One of a number of simple proteins (often found in the cell nucleus); contains a high proportion of basic amino acids; soluble in water, dilute acids, and alkalies; and not coagulable by heat; for example, the proteins associated with nucleic acids in the nuclei of plant and animal tissues. They constitute about half the mass of the chromosomes of eukaryotic cells.

histone

/his·tone/ (his´tōn) a simple protein, soluble in water and insoluble in dilute ammonia, found combined as salts with acidic substances, e.g., the protein combined with nucleic acid or the globin of hemoglobin.

histone

(hĭs′tōn′)
n.
Any of several basic proteins found in association with the DNA in the chromatin of eukaryotes.

histone

[his′tōn]
Etymology: Gk, histos, tissue
any of a group of strongly basic, low-molecular weight proteins that are soluble in water and insoluble in dilute ammonia and combine with DNA to form nucleoproteins. They are found in the nucleus of eukaryotic cells, where they form a complex with DNA in the chromatin and function in regulating gene activity. See also nucleosome.

his·tone

(his'tōn)
One of a number of simple proteins (often found in the cell nucleus) containing a high proportion of basic amino acids, are soluble in water, dilute acids, and alkalies, and are not coagulable by heat.

histone

a type of simple protein that is usually basic and tends to form complexes with nucleic acids (e.g. DNA) forming NUCLEOSOMES. CHROMOSOMES of EUKARYOTES contain large quantities of histones which may regulate DNA functioning in some way. The five major histones are represented as: H1, H2A, H2B, H3 and H4.

histone

a simple protein, soluble in water and insoluble in dilute ammonia, found combined as salts with acidic substances, such as in DNA where they have a structural and functional role.

histone acetylase, histone deacylase
enzymes responsible for the reversible acylation of four lysine residues near the N-terminus of histone H4.