CXCL12

(redirected from HIRH)
Also found in: Acronyms.

CXCL12

A gene on chromosome 10q11.1 that encodes a stromal cell-derived alpha chemokine of the intercrine family which, once bound to its receptor, CXCR4, activates lymphocytes, an interaction that has been implicated in the metastasis of breast and other cancers.

Molecular pathology
CXCL12 mutations are associated with resistance to HIV-1 infections.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
At the first rally held in Gobar in April 2011, Hirh witnessed Assad's troops shoot demonstrators.
Hirh had worked with his family's construction business but when the conflict erupted, he took photos and videos of events for TV news channels Al Jazeera and Al Arabiya.
Hirh managed to flee Syria with the help of a brother who had contacts with the Assad regime.
Hirh was not reunited with Iman and their three-year-old twin boys Bassil and Bashir until more than four months later, on May 12, 2012.