UBE2A

(redirected from HHR6A)

UBE2A

A gene on chromosome Xq24 that encodes a member of the E2 ubiquitin-conjugating enzyme family required for post-replicative repair of UV-damaged DNA.

References in periodicals archive ?

In humans, the yeast homologous Rad6 gene is duplicated and the proteins encoded by the two genes HHR6A (or Rad6A) and HHR6B (Rad6B) from chromosomes Xq24-q25 and 5q23-q31, respectively, share 95% identical amino acid residues [24].

Melanoma development and progression are associated with Rad6 upregulation and [beta]-catenin relocation to the cell membrane

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