DAX1

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DAX1

A gene (DSS-AHC critical region on the X chromosome, gene 1—formally known, per HUGO nomenclature, as NR0B1) located on chromosome Xp21.3 that encodes a protein containing a DNA-binding domain, which acts as a dominant-negative regulator of transcription mediated by the retinoic acid receptor. DAX1 also acts as an anti-testis gene by antagonising SRY.

Molecular pathology
DAX1 mutations cause both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
References in periodicals archive ?
Under his leadership, HHG has assembled a new management team of industry leaders, completely transformed the assets acquired from Furniture Brands and positioned the Company for the next phase of growth.
Work was discussed and evaluated throughout the summer and fall by Wright and members of the HHG office.
We will build on our heritage of providing industry standard software for mid-to-large commercial carriers and shippers, providing the same HHG mileage routing functionality coupled with features that our smaller sized customers have been asking for.
Before joining HHG, Falzone worked with US Trust-Bank of America and Wells Fargo.
It is a fact that the HHG moving industry has seen a reduction in its driver population since the beginning of the recession in 2008.
A tollgate review is regularly scheduled with appointed supervisors from FISC San Diego as well as the HHG team to track progression.
As an Enterprise Architect with an extensive history of solution architecture and design, HHG is the perfect fit.
Program Director, JPMO, HHG Systems, Acquisition Directorate, USTRANSCOM
Barbara brings a unique skill set that fits perfectly with the level of service our clients have come to expect from HHG," notes George Stapleton, CEO of HHG.
Paul brings a valuable new perspective and experience to the firm," notes Thomas Hynes, President of HHG.
KT will develop the u-Health Platform, which will store, manage and transmit data through the 3G HHG, as well as provide web service solutions and smartphone applications that will enable patients and health workers to better manage diabetes.
HHG experienced 6% annualized price deflation during the last half of the year, depressing gross margins and causing operating profit to drop significantly.