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A gene on chromosome 19q13.3 that encodes a Golgi membrane protein involved in synthesising an H-antigen precursor, which is required for the final step in synthesising soluble A and B antigens. FUT1 is one of two genes that encode galactoside 2-L-fucosyltransferase.
Molecular pathology
FUT1 mutations cause the H-Bombay blood group.
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