HES3

HES3

A gene on chromosome 1p36.31 that encodes a DNA-binding repressor of genes that require a basic helix-loop-helix (bHLH) for their transcription. This transcription repression requires the formation of a complex with a co-repressor protein of the Groucho/TLE family.
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References in periodicals archive ?
conducted a direct reprogramming of hepatocytes and Blymphocytes in NSC by means of a cocktail of factors Brn2, Hes1, Hes3, Klf4, Myc, Notch1, NICD, PLAGL1, and Rfx4 [137].
Masjkur et al., "Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics," Scientific Reports, vol.