HEMPAS | definition of HEMPAS by Medical dictionary
Also found in: Acronyms
Acronym for h
ultinuclearity associated with p
erum. See: HEMPAS cells
HEMPAS Hereditary erythrocytic multinuclearity with positive acidified serum lysis, Congenital dyserythropoietic anemia, type II An AR condition characterized by an IgM autoantibody against the RBC's i antigen–'anti-HEMPAS', an antigen is present in1⁄3 of normal sera Clinical Mild or subclinical congenital dyserythropoietic anemia Lab Normocytic aniso-poikilocytosis and multi-nucleated erythroblasts; ↑ agglutinability of serum with anti-i antibodies Treatment None; splenectomy is partially beneficial. See CDA.