HELLP syndrome


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HELLP syn·drome

type of severe preeclampsia involving hemolysis, elevated liver function, and low platelets.

HELLP syndrome

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abbreviation for a form of severe preeclampsia, a hypertensive complication of late pregnancy. The letters stand for hemolysis, elevated liver function, and low platelet level.
A condition linked to eclampsia or severe pre-eclampsia, which is characterised by the acronym HELLP:
Hemolysis
Elevated Liver function tests
Low Platelets
Eclampsia may transiently worsen after delivery; other symptoms include blood pressure 160 systolic and/or 110 diastolic, urinary volume 400 mL/24 hours, nonspecific cerebral abnormalities, pulmonary edema, cyanosis
Lab Proteinuria 5 g/24 hours, schistocytes (RBCs sheared and fragmented by intravascular fibrin deposition), increased LFTs (ALA, AST, ALT, BR) increased PT; aPTT, normal fibrinogen levels

HELLP syndrome

Obstetrics A condition linked to eclampsia or severe pre-eclampsia, characterized by the acronym: Hemolysis, Elevated Liver function tests, Low Platelets, which may transiently worsen after delivery; other Sx include BP ≥ 160 systolic and/or 110 diastolic, urinary volume ≤ 400 mL/24 hrs, nonspecific cerebral abnormalities, pulmonary edema, cyanosis Lab Proteinuria ≥ 5 g/24 hrs, schistocytes–RBCs sheared and fragmented by intravascular fibrin deposition, ↑ LFTs–ALA, AST, ALT, BR, ↑ PT; aPTT, normal fibrinogen levels. See MTP complex.

HELLP syndrome

Acronym for haemolysis, elevated liver enzymes, low platelet syndrome.
References in periodicals archive ?
This case illustrates the importance of eliciting a menstrual history in women with thrombocytopenia as a clue to the possibility of HELLP syndrome in early pregnancy.
Brenner B, Lanir N, Thaler I: HELLP syndrome associated with factor V R506Q mutation.
Current treatment options for HELLP syndrome include administration of plasma volume expansion, thrombolytic agents, immunosuppressive agents, and exchange plasmapheresis.
About 1 in 10 patients with preeclampsia develop HELLP syndrome, characterized by hemolysis, elevated liver enzymes, and low platelet counts.
There are several types of preeclampsia, including HELLP syndrome, a particularly dangerous variant.
Hepatic infarcts in pregnancy are mostly secondary to APS (Anti-Phospholipid Syndrome), HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) and preeclampsia.
LDH is elevated in women with ovarian dysgerminomas and is reliable in pregnancy outside of HELLP syndrome (hemolysis, elevated liver enzymes, low platelets).
Mrs Kivlehan suffered Hellp syndrome, a severe and rare variant of pre-eclampsia, in the days after the birth of the couple'son Dior, who was four last Sunday.
Disseminated Scedosporium apiospermum infection in a previously healthy woman with HELLP syndrome.
Gestational hypertensive diseases were also encountered; three cases of preeclampsia, one case of HELLP syndrome and two cases of gestational hypertension were observed.
This is precisely what happens to women who face the challenges of preeclampsia and HELLP syndrome during the middle to latter stages of pregnancy.