HELLP syndrome


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

HELLP syn·drome

type of severe preeclampsia involving hemolysis, elevated liver function, and low platelets.

HELLP syndrome

[help]
abbreviation for a form of severe preeclampsia, a hypertensive complication of late pregnancy. The letters stand for hemolysis, elevated liver function, and low platelet level.
A condition linked to eclampsia or severe pre-eclampsia, which is characterised by the acronym HELLP:
Hemolysis
Elevated Liver function tests
Low Platelets
Eclampsia may transiently worsen after delivery; other symptoms include blood pressure 160 systolic and/or 110 diastolic, urinary volume 400 mL/24 hours, nonspecific cerebral abnormalities, pulmonary edema, cyanosis
Lab Proteinuria 5 g/24 hours, schistocytes (RBCs sheared and fragmented by intravascular fibrin deposition), increased LFTs (ALA, AST, ALT, BR) increased PT; aPTT, normal fibrinogen levels

HELLP syndrome

Obstetrics A condition linked to eclampsia or severe pre-eclampsia, characterized by the acronym: Hemolysis, Elevated Liver function tests, Low Platelets, which may transiently worsen after delivery; other Sx include BP ≥ 160 systolic and/or 110 diastolic, urinary volume ≤ 400 mL/24 hrs, nonspecific cerebral abnormalities, pulmonary edema, cyanosis Lab Proteinuria ≥ 5 g/24 hrs, schistocytes–RBCs sheared and fragmented by intravascular fibrin deposition, ↑ LFTs–ALA, AST, ALT, BR, ↑ PT; aPTT, normal fibrinogen levels. See MTP complex.

HELLP syndrome

Acronym for haemolysis, elevated liver enzymes, low platelet syndrome.
References in periodicals archive ?
Approximately, one third of HELLP syndrome cases are diagnosed postpartum, (3,4) and two thirds are identified ante partum.
Remaining patients were terminated due to eclampsia, HELLP syndrome, IUD, foetal distress and renal failure.
In some Indian studies so far, although, the prognosis of partial HELLP syndrome is not as severe as the fully developed HELLP syndrome, still poor foetal outcome and number of caesarean section has been found to be significantly greater in comparison to the normal deliveries.
In pregnant women with PIH, there were 8 with placental abruption, 4 with hemorrhages, 2 with eclampsia and 4 with HELLP syndrome.
All viral markers were negative and patient had no manifestation of pre-eclampsia and HELLP syndrome throughout pregnancy.
6] In these cases, pathological causes of increased destruction or utilisation of platelets such as preeclampsia/eclampsia, the HELLP syndrome (haemolysis, elevated liver enzymes and low platelet count), and microangiopathies such as thrombotic thrombocytopenic purpura, (auto)immune thrombocytopenic purpura, haemolytic uraemic syndrome and haemolysis are likely.
A blogging friend of mine tragically lost her baby son Hugo nearly two years ago now when she developed the life threatening HELLP syndrome and he had to be delivered at 24 weeks.
Tiny Jack and Oliver Hancher were born eight weeks early at Birmingham Women's Hospital, after mum Abigail developed life-threatening pre-eclampsia and HELLP syndrome.
HELLP syndrome was first mentioned in 1954 by Prichard and was described clinically in detail in 1982 by Weinstein.
Leukocytosis is proportional to HELLP syndrome severity: evidence for an inflammatory form of preeclampsia.