EPHA3

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EPHA3

A gene on chromosome 3p11.2 that encodes a member of the ephrin-A receptor subfamily of receptor tyrosine kinases, which promiscuously bind membrane-bound ephrin-A family ligands residing on adajcent cells, leading to contact-dependent bidirectional signalling into neighbouring cells. EPHA3 mediates developmental events, especially in the nervous system—once activated by EFNA5, it regulates cell–cell adhesion, cytoskeletal organisation and cell migration. It plays a role in cardiac cell migration and differentiation, and it regulates formation of the atrioventricular canal and septum during development. It is involved in the retinotectal mapping of neurons and may control the segregation—but not the guidance—of motor and sensory axons during neuromuscular circuit development.
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Wild type HEK 293 cells were seeded into T75 flask and grown to about 80% confluency.
The following pictures represent the morphological differences between transduced HEK cells that were treated with TPA and DMSO.
Human breast adenocarcinomas MDA-MB 231 and BT 474, Caucasian prostate adenocarcinoma PC 3, and two non-tumorigenic, CHO and HEK 293, cell lines were treated with various concentrations (10-150 [micro]M) of isofuranodiene for up to three days and the effect on cell viability was examined in comparison with growth control in MeOH (GCM).
Human embryonic kidney (HEK) cell line is widely used for viral transfection studies and for production of therapeutic proteins by pharmaceutical companies.
Both HEK 293T and HepG2 cells were counted on micropattern spots at four time points (12 hr, 36 hr, 60 hr and 84 hr).
Starting February 15, 2013, nominal coupon bonds issued by ARTSAKH HEK ojsc were listed and included in the Bbond list
British scholars and researchers in nursing Moule and Hek introduce research concepts and methods to qualified health and social care practitioners and students who have no previous experience with research.
As soon as Diab left the 4 Cats, she acted in a local series titled "Ad-Duniya Hek," which aired during Ramadan in 2010.
As part of the Hunt for the Exomoons with Kepler (HEK) project, the team analyzed recently released Kepler data and identified systems with transiting planets that show transit variations indicative of hidden companions, such as unseen moons or planets.
"A critical aspect of this capability is its compatibility with CHO cells, eliminating the need to begin protein expression efforts in HEK cells or other irrelevant cell lines."
These properties were substantiated in the previously reported pancreatic cancer clinical trials that employed human embryonic kidney (HEK 293) cells.