DSG2(redirected from HDGC)
Also found in: Acronyms.
DSG2A gene on chromosome 18q12.1 that encodes desmoglein 2, a calcium-binding transmembrane glycoprotein component of desmosomes expressed in the colon, in colorectal carcinoma, and in other simple and stratified epithelial-derived cell lines.
Defects in DSG2 cause arrhythmogenic right ventricular dysplasia, type 10, and susceptibility to cardiomyopathy dilated type 1BB.
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