ASAH2

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ASAH2

A gene on chromosome 10q11.23 that encodes an amidohydrolase which hydrolyses ceramide into sphingosine and free fatty acid, acting as a key regulator of sphingolipid-signalling metabolites by generating sphingosine at the cell surface. It represses apoptosis by reducing C16-ceramide (preventing ceramide-induced apoptosis) and by generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate.
References in periodicals archive ?
HCD involves deeply understanding individuals' unmet needs and using these insights to improve service design and delivery.
HCD and HFD groups had free access to food while the amount of food was reduced 50% for HCD-FR or HFD-FR for 56 days.
Diagnosis of HCDs can be challenging because of their rarity and nonspecific clinical and laboratory findings.
After 2 weeks, the body weight gain was 0.76, 0.92, and 2.55 g for the LoPYC+ HCD, HiPYC + HCD, and blank groups, respectively (Figure 1(a)).
After two weeks without word from either HCD or JFC, Cadag took to the Commission on Human Rights at NCR and submitted the complaint letter, emails, and texts with Angsico.
Several surgical exposure variables associated with increased odds of case status were further tested for association with exposure to cardiopulmonary bypass with HCD using the Fisher exact test.
Imdad Aslam, Director Digital Financial Services at Karandaaz Pakistan closed the session, stating "I believe that the HCD based design will allow the MFS industry in Pakistan to substantially augment its services and expand them to low literate financially excluded people, especially women".
Rats fed a HCD resulted in significant increase in total cholesterol and LDL levels compared to the SCD.
Rats fed with HCD for 6 weeks had significant increase in ALT (Figure 1(a)) and AST (Figure 1(b)) levels (P < 0.001) compared to control and HCD + Rutin groups.
Birds fed HCD had significantly higher bodyweight (P < 0.01) than those fed RSD at 2 through 7 WOA (Figure 1).
The inaugural ASTD-STADA Asia-Pacific (ASAP) 2011 Conference, launching on 16-18 November at Marina Bay Sands, will address the region's evolving human capital development (HCD) landscape and discuss key strategies for leading Asian companies into the future.
Eventually she was able to confirm to her caregiver, "My teeth hurt." Sunrise contacted House Call Dentist (HCD) and arranged a dental examination for Jeane--right in her very own room.