SERPIND1

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SERPIND1

A gene on chromosome 22q11.21 that encodes a member of the serine protease inhibitor (serpin) family that rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. SERPIND1 shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily.

Molecular pathology
SERPIND1 mutations are associated with heparin cofactor-II deficiency.
References in periodicals archive ?
Table VII reports the results of the subsample analysis, summarizing the coefficients on UWIB and IB across regressions of the two dependent variables (HC1 and HC2) with style and year fixed effects.
Under the agreement with Northstar, HC2 Network will acquire Northstar's broadcast television stations, which carry Azteca America programming.
Related: HC2, Aegon let investors peek into long-term care insurance units
Positivity for HC2 was shown in 544 (8.6%) specimens and high risk HPV types for real-time PCR were identified in 593 (9.4%) specimens.
However, when performance of the 3 media types was compared within each category of testing platform (Table 2), only HC2, laboratory-developed tests, and other (noncommercial) methods were shown to perform equally well in all 3 media, whereas there were significant performance differences for Cervista and unspecified commercial kits, depending on the medium used: Cervista underperformed in SurePath and Digene media compared with ThinPrep (both P < .001), and unspecified commercial kits underperformed in ThinPrep compared with SurePath (P < .001).
3) generan algun interrogante sobre si no se estarian trasladando; pero la referencia directa de Hatcher sobre que la serie de robustus se logro antes de cambiar el campamento aguas arriba del rio Tucu Tucu, inequivocamente alude al HC2. En consecuencia, la localidad tipica de C.
Relative clinical sensitivity and clinical specificity are calculated in comparison to performance characteristics of the clinically validated test HC2: RealTime values below 1.00 favor the comparator, and values above 1.00 favor RealTime.
More than 8,600 Danish women, 20 to 29 years old at enrollment, were tested twice, 2 years apart, for HPV by the Hybrid Capture 2 High-Risk (HC2 HR) HPV DNA Test (Qiagen) and byline-blot assays for type-specific HPV.
Both amplification methods were tested in comparison and simultaneously with the FDA approved HC2 assay.
According to the formulations listed in Table 1, appropriated amounts of Catalysts I and II were blended at room temperature to form a hybrid catalyst (coded as HC1, HC2, and HC3, respectively), the probable reaction mechanism is proposed as shown in Scheme 4 based on the researches by Augstin's group (17).
One noticeable decline in the overall share of NHS eye examinations has been in those people on low income certificate holders (HC2) in the last ten years, with 92,000 people in this category having a NHS sight test in 2010-2011, or 0.8% of the total number of sight tests carried out (in 20022003 it was 1.7%).
The quarter-final draw will be: CC1 v CC5, CC2 v HC3, CC3 v HC2, CC4 v HC1.