SCN2A

(redirected from HBSCII)

SCN2A

A gene on chromosome 2q24.3 that encodes a large alpha subunit of a transmembrane glycoprotein complex, which forms a voltage-gated sodium channel. The SCN2A protein product is expressed in muscle and brain.

Molecular pathology
SCN2A mutations are linked to various seizure disorders.
References in periodicals archive ?
(a) TTX [alpha] subunit Older names sensitivity [Na.sub.v] 1.1 Rat I, HBSCI, GPBI, TTX-S SCN1A [Na.sub.v] 1.2 Rat II, HBSCII, HBA TTX-S [Na.sub.v] 1.3 Rat III TTX-S [Na.sub.v] 1.4 SkM1, [micro]1 TTX-S [Na.sub.v] 1.5 SkM2, H1 TTX-R [Na.sub.v] 1.6 NaCh6, PN4, Scn8a, TTX-S Cerlll [Na.sub.v] 1.7 NaS, hNE-NA, PN1 TTX-S [Na.sub.v] 1.8 SNS, PN3, NaNG TTX-R [Na.sub.v] 1.9 NaN, SNS2, PN5, TTX-R NaT, SCN12A [Na.sub.x] [Na.sub.v] 2.1, [Na.sub.v] 2.3 Na-G, ?