H3 receptor


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H3 receptor

, histamine H3 receptor
A presynaptic receptor in the CNS that controls the release of histamine and other neurotransmitters, including acetylcholine, dopamine, and norepinephrine. It influences arousal and sleep, cognition, attention, and other body functions.

H3 receptor

A presynaptic receptor in the central nervous system that controls the release of histamine and other neurotransmitters, including acetylcholine, dopamine, and norepinephrine. It influences arousal and sleep, cognition, attention, and other body functions.
Synonym: histamine H3 receptor
See also: receptor
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References in periodicals archive ?
The scientists suggest that the presence of the H3 receptors on the surface of the same cells that release histamine could indicate a feedback mechanism in which the receptors shut down histamine release when the substance reaches a certain level.
H1 and H2 receptors potentiate excitatory inputs while H3 receptors down regulate histamine synthesis and release as well as the release of other neurotransmitters (3).
Evotec said today that it has successfully identified and optimised H3 receptor antagonists through to preclinical development.
Small molecule drugs developer Evotec AG (Frankfurt:EVT) declared on Tuesday that the company will receive EUR1.5m of research funding to advance its H3 receptor antagonist programme into the clinic.
H3 receptors are presynaptic and mediate the inhibition of release of histamine involving G-protein.