H2-receptor antagonist


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H2-receptor antagonist

Any of the drugs that inhibit gastric acid secretion by blocking the effects of histamine or acetylcholine on receptors found on parietal cells. Such drugs are used to treat peptic ulcers and gastroesophageal reflux disease.
Synonym: H2 blocker
See also: antagonist
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These include hyperalimentation, corticosteroids, H2-receptor antagonists, antibiotics, acid suppression, Cromolyn Sodium, anabolic steroids, surgery, and combinations of these therapies (7).
Proctocolectomy for persistent haematochezia in a patient with Cronkhite-Canada syndrome
Published in the journal Clinical Gastroenterology and Hepatology, the study showed that patients who were given prescriptions for proton pump inhibitors (PPIs) tended to be more satisfied than those given H2-receptor antagonists.
Medication type, doctors' bedside manner key to GERD patients' satisfaction
It also protects against ulcers, reducing total gastric juice volume as H2-receptor antagonists (e.g., Zantac, Pepcid, Tagamet) do, but without disturbing pepsin-pH interaction.
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