H2-receptor antagonist


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H2-receptor antagonist

Any of the drugs that inhibit gastric acid secretion by blocking the effects of histamine or acetylcholine on receptors found on parietal cells. Such drugs are used to treat peptic ulcers and gastroesophageal reflux disease.
Synonym: H2 blocker
See also: antagonist
References in periodicals archive ?
467, 2005) warns against using histamine H2-receptor antagonists (for example, Zantac) when taking the HIV protease inhibitor Lexiva.
Treatment of reflux oesophagitis resistant to H2-receptor antagonists.
H2-receptor antagonists have also been prescribed for treating NSAID-induced gastric injury, but with limited success.