H2-receptor antagonist


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H2-receptor antagonist

Any of the drugs that inhibit gastric acid secretion by blocking the effects of histamine or acetylcholine on receptors found on parietal cells. Such drugs are used to treat peptic ulcers and gastroesophageal reflux disease.
Synonym: H2 blocker
See also: antagonist
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467, 2005) warns against using histamine H2-receptor antagonists (for example, Zantac) when taking the HIV protease inhibitor Lexiva.
Drugs for GI upset may interact with HIV protease inhibitors
Treatment of reflux oesophagitis resistant to H2-receptor antagonists.
Treatment of laryngopharyngeal reflux
H2-receptor antagonists have also been prescribed for treating NSAID-induced gastric injury, but with limited success.
Sucampo Completes Enrollment in Its Phase 2 Trial of Cobiprostone for the Prevention of NSAID-Induced Ulcers

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