H2-receptor antagonist | definition of H2-receptor antagonist by Medical dictionary
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Any of the drugs that inhibit gastric acid secretion by blocking the effects of histamine or acetylcholine on receptors found on parietal cells. Such drugs are used to treat peptic ulcers and gastroesophageal reflux disease. Synonym: H2 blocker
References in periodicals archive
467, 2005) warns against using histamine H2-receptor antagonists
(for example, Zantac) when taking the HIV protease inhibitor Lexiva.
Treatment of reflux oesophagitis resistant to H2-receptor antagonists
have also been prescribed for treating NSAID-induced gastric injury, but with limited success.