H2 receptor antagonist


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H2 receptor antagonist

an agent that blocks the action of histamine by competitive binding to the H2 receptor. It is used to inhibit gastric secretion in the treatment of peptic ulcer.
References in periodicals archive ?
63 per 20 mg capsule [Cardinale, 1996]) and limited pediatric data, it is often reserved as second line treatment for patients unresponsive to the H2 receptor antagonists.
In Phase III alone, there are 10 me-too molecules and seven product extensions including H+/K+ ATPase inhibitors and H2 receptor antagonists.
He also indicated that the dyspeptic complaints were not improved by use of H2 receptor antagonists or proton pump inhibitors (PPIs).
It is expected that statins, proton-pump inhibitors (PPIs) and H2 receptor antagonists will follow, with all other reference groups due to be included by the end of 2008.
The combined market for H2 receptor antagonists and proton pump inhibitors, the two major GORD therapies currently in the marketplace, is estimated to be worth around US$25 billion.
on medications such as H2 receptor antagonists and proton pump inhibitors, a significant number of patients seek a permanent solution, as they are either unwilling to take chronic lifelong medications, or they are becoming increasingly unresponsive to high dose medications.