Hürthle cell tumor

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Hürthle cell tumor

a new growth of the thyroid gland composed wholly or predominantly of Askanazy cells (Hürthle cells) having abundant granular, eosinophilic cytoplasm. Such tumors are usually benign (Hürthle cell adenoma) but on occasion may be locally invasive or may rarely metastasize (Hürthle cell carcinoma).

Hürth·le cell tu·mor

(hērt'lĕ sel tū'mŏr)
A neoplasm of the thyroid gland composed of polyhedral acidophilic cells, thought by some to be oncocytes; it may be benign or malignant, the behavior of the latter depending on the general microscopic pattern, whether follicular, papillary, or undifferentiated.
See also: Hürthle cell adenoma
Synonym(s): Hürthle cell carcinoma.


Karl W., German histologist, 1860-1945.
Hürthle cell - a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, e.g., in Hashimoto disease. Synonym(s): Askanazy cell
Hürthle cell adenoma - a follicular adenoma of the thyroid in which the epithelium has undergone metaplasia into Hürthle cells.
Hürthle cell carcinoma - Synonym(s): Hürthle cell tumor
Hürthle cell tumor - neoplasm of the thyroid gland. Synonym(s): Hürthle cell carcinoma