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a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, for example, in Hashimoto disease.
Synonym(s): Askanazy cell
A large granular cell found in pathological sections in some thyroid diseases.
See also: Hürthle, Karl W.
Hürthle,Karl W., German histologist, 1860-1945.
Hürthle cell - a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, e.g., in Hashimoto disease. Synonym(s): Askanazy cell
Hürthle cell adenoma - a follicular adenoma of the thyroid in which the epithelium has undergone metaplasia into Hürthle cells.
Hürthle cell carcinoma - Synonym(s): Hürthle cell tumor
Hürthle cell tumor - neoplasm of the thyroid gland. Synonym(s): Hürthle cell carcinoma
large oxyphilic, eosinophilic cells found in the thyroid gland. They are metabolically altered follicular cells which accumulate large numbers of mitochondria. See also Hürthle cell tumor (below).
Hürthle cell tumor
a new growth of the thyroid gland composed wholly or predominantly of large cells (Hürthle cells) having abundant granular, eosinophilic cytoplasm. Such tumors are usually benign (Hürthle cell adenoma) but on occasion may be locally invasive or may rarely metastasize (Hürthle cell carcinoma, or malignant Hürthle cell tumor). Called also oxyphilic adenoma of thyroid gland.