gene-environment interaction

(redirected from GxE interaction)

gene-environment interaction

A term used to indicate that an effect is due to a mixture of environmental factors (nurture) and genetic factors (nature). Most traits show gene-environment interactions, such as myopia, IQ test results, skin colour etc. Blood type and iris colour are predominantly genetically transmitted, whereas language is predominantly environmental. See biological-statistical theory; nativist theory.
References in periodicals archive ?
The stability and adaptability of a Sweet sorghum cultivar during growth periods is determined in part by the GxE interaction, and both stability and adaptability appear to decrease as the effects of these interactions become larger.
The GxE interaction is defined as the differential of the genotype response in connection with the environmental variation (COUTO et al., 2015).
This is a classic example of GxE interaction, where genes alone are insufficient to produce a psychiatric disorder without environmental events interacting with them and triggering the psychopathology.
The limitations of the present study include the small number of female mice and lack of a control group to evaluate possible stressful effects of IP injections in this model of GxE interaction. Future studies will address these limitations.
It may be observed that the mean squares presented a significant difference for all studied characteristics in the GxE interaction by the F test (Table 2).
A possible strategy is the use of the GxE interaction, which could probably increase the technological, culinary and nutritional quality values of the new genotype and also meet farmers' specific demands.
The first four terms of the AMMI analysis were significant, explaining 84.72% of the GxE interaction sum of squares (45.97%, 24.12%, 12.87%, and 1.76%, for the 1st, 2nd, 3rd and 4th interaction principal component axis, respectively), with 62% of the GxE interaction degrees of freedom, and leaving a non-significant residual (Table 1).
(192) A statistical GxE interaction has been consistently found in all major adoption studies of criminal convictions, such that the genetic predispositions, indicated by biological-parent antisocial behavior, present the greatest risk to the adopted offspring in the presence of adverse environmental conditions, indicated by adoptive-parent antisocial behavior.
The females and males x females partitions of GxE interaction were not significant, suggesting that meaningful comparisons between the MSC hybrid and the SC hybrid counterparts can be made across environments.
Understanding the contributions of GxE interaction effects to the risk for and development of alcohol dependence and coexisting disorders is of paramount importance.
Using this model, we found suggestive evidence that a GxE interaction may exist because a positive endotoxin-WBC relationship was found only in TLR4 variant noncarriers (interaction p-value = 0.15; Table 5).