RhoA is a member of the Ras superfamily of small GTP-binding proteins
, which has been demonstrated to contribute to profibrotic signaling and fibronectin production in diabetic kidney and interfering with VEGF-mediated endothelial cell function [36-38].
Yu et al., "The small GTP-binding proteins rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway," Cell, vol.
Hall, "Activation of the small GTP-binding proteins rho and rac by growth factor receptors," Journal of Cell Science, vol.
(1977) GTP-binding proteins in mem branes and the control of adenylate cyclase activity.
subunits of GTP-binding proteins activate the muscarinic KD channel in heart.
CgtA is a highly conserved essential GTP-binding protein
, coded by the cgtA gene, belonging to Obg subfamily in prokaryotes (8).
Chadi et a1 (22), reported that compound 48/80 activated mast cell phospholipase D (PLD) via heterotrimeric GTP-binding proteins
In previous studies, we and others have demonstrated that nitric oxide is also important in regulating motility in sea urchin sperm, and we have found further that this process is likely to be dependent on the activity of GTP-binding proteins
Cytotoxic necrotizing factor type 2 produced by virulent: Escherichia coli modifies the small GTP-binding proteins
Rho involved in assembly of actin stress fibers.
Small GTP-binding proteins
(G-proteins) of the Rho family have been shown to regulate cytoskeleton reorganization, whereas G-proteins of the Rab family have been shown to regulate intracellular trafficking and vesicle transport (1).
A protein like that could interact through GTP-binding proteins
to stimulate polymerization in the immediate vicinity.
Identification of the subunits of GTP-binding proteins
coupled to somatostatin receptors.