somatostatin

(redirected from Growth Hormone Inhibatory Hormone)
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somatostatin

 (SRIF, SS) [so″mah-to-stat´in]
a cyclic tetradecapeptide hormone and neurotransmitter that inhibits the release of peptide hormones in many tissues. It is released by the hypothalamus to inhibit the release of growth hormone (GH, somatotropin) and thyroid stimulating hormone (TSH) from the anterior pituitary; it is also released by the delta cells of the islets of Langerhans in the pancreas to inhibit the release of glucagon and insulin and by the similar D cells in the gastrointestinal tract.

so·ma·to·stat·in

(sō'mă-tō-stat'in), [MIM*182450]
A tetradecapeptide capable of inhibiting the release of somatotropin by the anterior lobe of the pituitary gland; somatostatin has a short half-life; it also inhibits the release of insulin, glucagon, and gastrin. Used in the treatment of acromegaly, gigantism, and pancreatic tumors.
[somatotropin + G. stasis, a standing still, + -in]

somatostatin

(sō-măt′ə-stăt′n, sō′mə-tə-)
n.
A polypeptide hormone produced chiefly by the hypothalamus that inhibits the secretion of various other hormones, such as somatotropin, glucagon, insulin, thyrotropin, and gastrin.

so·ma·to·stat·in

(sō'mă-tō-stat'in)
A tetradecapeptide capable of inhibiting release of somatotropin, insulin, and gastrin.
Compare: bioregulator
Synonym(s): growth hormone-inhibiting hormone, somatotropin release-inhibiting hormone.
[somato- + G. stasis, a standing still, + -in]

somatostatin

a hormone of the hypothalamus that inhibits the release of growth hormone from the pituitary gland.

so·ma·to·stat·in

(sō'mă-tō-stat'in) [MIM*182450]
Tetradecapeptide capable of inhibiting release of somatotropin by anterior lobe of pituitary gland.
[somatotropin + G. stasis, a standing still, + -in]
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