HSPD1

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HSPD1

A gene on chromosome 2q33.1 that encodes a mitochondrial protein of the chaperonin family, which may function as a signalling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in mitochondria. HSPD1 is adjacent to a related gene; the region between the two acts as a bidirectional promoter.

Molecular pathology
HSPD1 mutations cause autosomal recessive spastic paraplegia 13.

References in periodicals archive ?

Aiming to search for accurate methods to identify strains showing atypical results in the coagulation assays, we estimated the identification potential of four different techniques: Matrix-Assisted Laser Desorption Ionization-Times of Flight Mass Spectometry (MALDI-TOF), PCR-restriction fragment length polymorphism (PCR-RFLP) of the chaperonine gene groEL, and DNA sequencing of the 16S rRNA and elongation factor Tu gene tuf

Accurate identification of atypical Staphylococcus chromogenes plasma-clotting strains causing bovine mastitis/Identificacao acurada de cepas atipicas de Staphylococcus chromogenes que coagulam o plasma envolvidas com mastite bovina

DNA'lardan L.acidophilus ve L.casei miktarlarinin saptanmasi icin tablo 1'deki Hsp60, groEL bolgesi spesifik primer ve problar kullanilarak LightCycler 480 II (Roche Diagnostics, Mannheim, Almanya) real-time PCR sisteminde, Fast Start Essential Probe Master Mix kiti (Roche Diagnostics GmBH, Mannheim Almanya) ile her bir reaksiyona tablo 2'deki reaktif miktarlari yuklenerek uretici direktifleri dogrultusunda calisma yapildi (11, 12).

Tip 1 Diyabet Hastalarinin Bagirsak Mikrobiyotasinda Lactobacillus Casei ve Lactobacillus Acidophilus Miktarinin Arastirilmasi/Investigation of Lactobacillus Casei and Lactobacillus Acidophilus Amount at Gut Microbiota from Adult Type 1 Diabetes Mellitus Patients

Versatile roles of the chaperonin GroEL in microorganism-insect interactions.

Shifting the Balance: Heat Stress Challenges the Symbiotic Interactions of the Asian Citrus Psyllid, Diaphorina citri (Hemiptera, Liviidae)

GroEL, DnaK, GroES, Tig, DnaJ and GrpE are major cytoplasmic chaperones in E.

Soluble Expression of Humanized Anti-CD20 Single Chain Antibody in Escherichia coli by Cytoplasmic Chaperones Co-expression

This increased thermal tolerance is partially due to the activation of conserved heat shock proteins (Hsps) (e.g., DnaK and GroEL) under sublethal heat temperatures (Doyle et al., 2001; Ferreira et al., 2001; Hill et al., 2002).

DIFFERENCES IN SURVIVAL OF HEAT STRESS ADAPTED CELLS OF Listeria monocytogenes EGD (BUG 600) IN DISINFECTANTS AND ESSENTIAL OILS

We confirmed EMLA positivity of the samples by amplifying and sequencing the EMLA citrate synthase (gltA) and heat shock protein (groEL) genes (3).

Ehrlichia muris in Ixodes cookei Ticks, Northeastern United States, 2016-2017

A highly sensitive quantitative real-time PCR assay based on the groEL gene of contemporary Thai strains of Orientia tsutsugamushi.

Rapid Diagnosis of Tick-Borne Illnesses by Use of One-Step Isothermal Nucleic Acid Amplification and Bio-Optical Sensor Detection

Roseman et al., "ATP-bound states of GroEL captured by cryo-electron microscopy," Cell, vol.

Biophysical, Biochemical, and Cell Based Approaches Used to Decipher the Role of Carbonic Anhydrases in Cancer and to Evaluate the Potency of Targeted Inhibitors

The synthesis of DnaK and GroEL was induced during infection, evidenced by antibodies detected in sera from patients with S.

Adaptive Metabolism in Staphylococci: Survival and Persistence in Environmental and Clinical Settings

CpaB, CpaF/TadA, TadB, pilQ/Cpac, pilV, flp1, flp2 (genes associated with type IV pilus secretion), chemotaxis protein (MCP: methyl accepting chemotaxis protein, chemotaxis protein CheY), heat-shock protein (GroES and GroEL), cell wall-associated protein (wapA), host interaction (hit) locus orf.

Whole-Genome Sequencing and Comparative Genome Analysis Provided Insight into the Predatory Features and Genetic Diversity of Two Bdellovibrio Species Isolated from Soil

Identification of Salmonella isolated from poultry by MPCR technique and evaluation of their hsp groEL gene diversity based on the PCR-RFLP analysis.