(redirected from Gonadotrophs)


1. a type of basophil in the adenohypophysis whose granules secrete follicle-stimulating hormone and luteinizing hormone.
2. a gonadotropic substance.


/go·nado·trope/ (go-nad´ah-trōp) gonadotroph.

gonadotrope, gonadotrop, gonadotroph

a basophilic cell of the anterior pituitary specialized to secrete follicle-stimulating hormone or luteinizing hormone.
References in periodicals archive ?
In addition, the presence of ghrelin and its receptors has been reported in GnRH neurons (4) and gonadotrophs of pituitary (5-7).
Activin A and B are also members of the TGF-[beta] superfamily, and have a variety of actions in both embryonic and adult tissues, including tissue fate determination in vertebrate embryos, regulation of follicle-stimulating hormone biosynthesis in pituitary gonadotrophs, and regulation of gametogenesis in ovaries and testes (Welt et al.
Effects of toxic levels of lead on gene regulation in the male axis: increase in messenger ribonucleic acids and intracellular stores of gonadotrophs within the central nervous system.
24) However, prolonged stimulation of GnRH receptors leads to reduced numbers of receptors, blocking the action of GnRH pulses on the gonadotrophs, preventing the secretion of LH pulses and decreasing FSH secretion, leading to down-regulating the HPG axis.
1997) Pituitary gonadotrophs are strongly activated at the beginning of spermatogenesis in African catfish, Clarias gariepinus.
2000) observed cell-specific localization of guanylin in the juxtaneural pars tuberalis adjacent to nerve endings and blood vessels of the hypothalamo-pituitary portal system and in gonadotrophs cells within the distal pars tuberalis and ventrolateral region of the pars distalis.
Effects of an indigenous contraceptive herbal formulation on gonadotrophs of the pituitary gland of the rat.
Sensibilidad hipofiso-testicular del nativo normal de altura a la administracion de hormona liberadora de gonadotrophs.
Special cells inside the pituitary known as gonadotrophs produce hormones (specifically gonadotropin-releasing hormone and luteinizing hormone, or LH) that control ovulation and fertility.
The investigators focused on a class of pituitary cells called gonadotrophs, which secrete luteinizing hormone (LH), critical for ovulation and fertility.
These cells release GnRH into a portal vascular system that carries this peptide hormone to the anterior lobe of the pituitary gland where it induces release of LH and FSH from cells known as gonadotrophs.
Asubstance with hCG-like properties was 1st identified in the pituitary gland in 1976 and was subsequently localized to gonadotrophs (8).