GnRH stimulation test

GnRH stimulation test

Urology A test used to evaluate adequacy of testosterone production Ref range At 30–45 mins, serum LH levels ↑ 3 to 6 fold; FSH levels ↑ 20 to 50% Abnormal values ↑ LH and FSH in 1º testicular failure; normal to ↓ in hypothalamic or pituitary disease. See Testosterone.
Mentioned in ?
References in periodicals archive ?
3 U/L, the GnRH stimulation test was conducted; secondly, GnRH stimulation test: The stimulated peak value in the test can be used as diagnostic basis, the peak value referred to the maximum value of LH and FSH at each time-point in the stimulation test, which occurred at 60-120 min; for detection at 60 min, with immune chemiluminescence assay, when peak LH > 3.
The peak LH after GnRH stimulation test at 6 months after treatment in all patients of two groups was significantly decreased compared with that before the treatment, reached the prepubertal level (< 3.
Rosenthal recommended doing a GnRH stimulation test, which is also called a luteinizing hormone releasing factor (LRF) stimulation test.
The GnRH stimulation test correlates neither with testicular hypotrophy nor with long-term semen parameters and fertility.
In another study, we found abnormal results on GnRH stimulation tests in 30% of 104 teenagers with varicoceles but not in 10 control patients.
The objective of this research was to assess the cut-off values and the efficacy of GnRH stimulation test in the diagnosis of delayed puberty in both males and females.
The GnRH stimulation test appears to be the most widely used test in the differential diagnosis of IHH and CDP.
The area under the ROC (AUC) was computed to assess the predictive diagnostic value of the GnRH stimulation test and select the best predictors.
Basic serum LH and FSH levels had the greatest AUCs and were the most effective predictors for diagnosing IHH and CDP patients in females, meaning that the GnRH stimulation test is unnecessary in differentiating between IHH and CDP in female patients.
If the initial hormone profile does not fall into one of the general patterns of central or peripheral, overnight sampling of blood for LH/FSH and a GnRH stimulation test can be helpful.
As the basal hormonal profiles revealed typical secondary hypothyroidism and hypogonadism, no TRH and GnRH stimulation tests were performed.
Pituitary apoplexy probably due to TRH and GnRH stimulation tests in a patient with acromegaly.