GnRH stimulation test

GnRH stimulation test

Urology A test used to evaluate adequacy of testosterone production Ref range At 30–45 mins, serum LH levels ↑ 3 to 6 fold; FSH levels ↑ 20 to 50% Abnormal values ↑ LH and FSH in 1º testicular failure; normal to ↓ in hypothalamic or pituitary disease. See Testosterone.
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A GnRH stimulation test (2.5 [micro]/kg, maximum 100 [micro], IV) was performed in all probands.
The peak LH after GnRH stimulation test at 6 months after treatment in all patients of two groups was significantly decreased compared with that before the treatment, reached the prepubertal level (< 3.3 U/L).
Furthermore, in a study of 33 patients above 15 years of age, with transfusion-dependent BTM and iron overload, anterior pituitary function (GnRH stimulation test) correlated well with MRI results.
Rosenthal recommended doing a GnRH stimulation test, which is also called a luteinizing hormone releasing factor (LRF) stimulation test.
Common indications for surgical intervention in the adolescent include discomfort or pain, size or grade of varicocele, an abnormal GnRH stimulation test, and hypotrophy or testicular disproportion, with the belief that varicocele represents a progressive disease process.
GnRH stimulation test was performed in all patients with early breast development.
The objective of this research was to assess the cut-off values and the efficacy of GnRH stimulation test in the diagnosis of delayed puberty in both males and females.
If the initial hormone profile does not fall into one of the general patterns of central or peripheral, overnight sampling of blood for LH/FSH and a GnRH stimulation test can be helpful.
In our previous study, high BMI was also associated with lower LH response to the GnRH stimulation test in boys with CPP (15).
A GnRH stimulation test was performed on the proband of the Family 1 by injecting 0.1 mg GnRH intravenously and drawing blood samples at 0, 15, 30, 45, 60, and 75 minutes for FSH and LH determinations.
Cranial magnetic resonance imaging was performed to exclude an organic lesion in cases diagnosed with early puberty using basal or peak LH level at the time of the GnRH stimulation test (18).
As the basal hormonal profiles revealed typical secondary hypothyroidism and hypogonadism, no TRH and GnRH stimulation tests were performed.