The rate of early LH surge is 20% in cycles in which no GnRH analog
is used (9).
Influence of GnRH analog
therapy on body mass in central precocious puberty.
Control of ovulation with a GnRH analog
in gilts and sows.
Combined therapy with GnRH analog
plus growth hormone in central precocious puberty.
Twenty-four-hour pattern of growth hormone (GH) concentration in the plasma of rats administered placebo, dalarelin and cetrorelix for: a) 2 months of GnRG analog administration, b) 3 months of GnRH analog
administration, c) 1 week after treatment discontinuation, d) 2 weeks after treatment discontinuation
The objective of the study was to evaluate the clinical efficacy and safety of domestic leuprorelin (GnRH analog
) in girls with ICPP.
works by competing occupied GnRH receptors, causing suppression of the gonads and amenorrhea in patients.
Twenty percent of hypothalamic GnRH-I secreting neurons possess CBj, and buserelin, a long acting GnRH analog
, increases [CB.sub.1] expression and inhibits those of GnRH-I .
Uncertainties about the benefits of GnRH analog
treatment on growth of children with CPP comes from the fact that there is no randomised controlled study on this respect.
[sup] However, this cut-off value is a little higher than other GnRH analog
stimulation tests, such as buserelin, nafarelin, leuprolide, and triptorelin.
Diamond therefore recommends prior treatment of late-stage endometriosis with GnRH analog
and possibly surgery when there is hope of reducing endometriomas, improving the environment for ART, and reducing toxicity associated with extensive endometriosis.