GYG1

(redirected from Glycogenin)
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GYG1

A gene on chromosome 3q24-q25.1 that encodes glycogenin 1, a glycosyltransferase which catalyses the formation of a short glucose polymer from uridine diphosphate (UDP) glucose in an autoglucosylation reaction. This reaction is followed by elongation and branching of the polymer, catalysed by glycogen synthase and branching enzyme, to form glycogen.

Molecular pathology
Defects of GYG1 cause glycogen storage disease type 15.
References in periodicals archive ?
This overexpression significantly increases basal glucose uptake and promotes the expression of genes associated with glucose uptake, such as glucose transporter 4 (GLUT4) and glycogenin [80].