McArdle disease

McArdle disease

 [mik-ar´d'l]

glycogen storage disease (type V), a condition in which deficiency of muscle phosphorylase results in accumulation of glycogen in skeletal muscles, with muscle cramps and a depressed blood lactate level during exercise. Called also myophosphorylase deficiency glycogenosis.

gly·co·ge·no·sis type 5

(glī'kō-jĕ-nō'sis tīp)

Disorder due to muscle glycogen phosphorylase deficiency, resulting in accumulation of glycogen of normal chemical structure in muscle tissue.
Synonym(s): McArdle disease, McArdle-Schmid-Pearson disease.

McArdle disease

(mak-ard'il)

[Brian McArdle, Brit. pediatrician, 1911–2002]

A glycogen storage disease caused by deficient myophosphorylase B (a muscle phosphorylase.)

Synonym: glycogen storage disease type V; muscle phosphorylase deficiency

McArdle,

Brian, English neurologist, d. 2002.

McArdle disease - Synonym(s): McArdle syndrome

McArdle syndrome - glycogenosis due to muscle glycogen phosphorylase deficiency, resulting in accumulation of glycogen of normal chemical structure in muscle. Synonym(s): Cori syndrome; McArdle disease; McArdle-Schmid-Pearson syndrome; type 5 glycogenosis

McArdle-Schmid-Pearson disease - Synonym(s): McArdle syndrome