glycosaminoglycan

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glycosaminoglycan

 [gli″kōs-ah-me″no-gli´kan]
any of the carbohydrates containing amino sugars occurring in proteoglycans, e.g., hyaluronic acid or chondroitin sulfate.

mu·co·pol·y·sac·cha·ride

(myū'kō-pol'ē-sak'ă-rīd),
General term for a protein-polysaccharide complex obtained from proteoglycans and containing as much as 95% polysaccharide; mucopolysaccharides include the blood group substances. A more modern term is glycosaminoglycan, because all of the known six classes contain major amounts of d-glucosamine and d-galactosamine.

glycosaminoglycan

(glī′kōs-ə-mē′nō-glī′kăn)
n. Abbr. GAG
Any of a group of unbranched polysaccharides with high molecular weight that contain amino sugars and often are attached to or form complexes with proteins. Also called mucopolysaccharide.

glycosaminoglycan

A complex macromolecule considered to be the 'glue' of the cornea. It is responsible for providing the plasticity and structural support needed for successful corneal function. Along with other molecules, it comprises the solid portion of the cornea (,22%, the remainder being water). The distribution and arrangement of glycosaminoglycans are responsible for corneal transparency and thickness.

Patient discussion about glycosaminoglycan

Q. Does GAG really help? My mother suffers from osteoarthritis, and after taking a lot of pain-killers someone offered us to try glycosaminoglycans. Does it really help? It’s quite expensive….

A. As far as I know it wasn’t proved in well-controlled trials to benefit the patients over placebo, so if it’s a consideration for you, I’m not sure it justifies the price. However, I’m only a lay-man, so consulting a professional (i.e. a doctor) is better.

More discussions about glycosaminoglycan
References in periodicals archive ?
Geria, L'Oreal's patented anti-aging molecule known as Pro-Xylane (the firm's name for xylose, a sugar molecule derived from the beechwood plant) has been clinically shown to reduce lines and wrinkles by boosting the production of glycoaminoglycans (GAGs) within the skin.
Heparin belongs to a family of complex carbohydrates known as glycoaminoglycans.
Shark cartilage is an excellent dietary source of chondroitin sulfate and other glycoaminoglycans that rebuild cartilage.
This cartilage is a matrix made up of collagen, hyaluronic acid (component of synovial fluid contained with the joint cavity) and glycoaminoglycans. Glucosamine is responsible for the synthesis of hyaluronic acid and glycoaminoglycans.