glycine cleavage complex

(redirected from Glycine synthase)

gly·cine cleav·age com·plex

a complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce CO2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinemia.
Synonym(s): glycine synthase
References in periodicals archive ?
The same set of enzymes is sometimes referred to as glycine synthase when it runs in the reverse direction to form glycine.