glycan

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Related to Glycans: glycosylation, Glycosaminoglycans

polysaccharide

[pol″e-sak´ah-rīd]

a carbohydrate which, on acid hydrolysis, yields many monosaccharides.

pol·y·sac·char·ide

(pol'ē-sak'ă-rīd),

A carbohydrate containing a large number of saccharide groups; for example, starch. Compare: oligosaccharide.

Synonym(s): glycan

Farlex Partner Medical Dictionary © Farlex 2012

glycan

(glī′kăn′, -kən)

Any of a group of sugar molecules that are freestanding as oligosaccharides or polysaccharides or are combined in conjugates, as in glycoproteins.

gly′cal (-kəl) adj.

pol·y·sac·char·ide

(pol'ē-sak'ă-rīd)

A carbohydrate containing a large number of saccharide groups (e.g., starch).
Compare: oligosaccharide
Synonym(s): glycan.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

pol·y·sac·char·ide

(pol'ē-sak'ă-rīd)

A carbohydrate containing a large number of saccharide groups (e.g., starch).
Synonym(s): glycan.

Medical Dictionary for the Dental Professions © Farlex 2012

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References in periodicals archive ?

On the other hand, the complexity of the glycan structures, the multiple substitutions at glycosylation sites, and the structural diversity associated with the protein backbone posed a giant challenge for the glycoprotein analysis.

Creative Biolabs Announces Custom Glycoprotein Synthesis and Glycoprotein Detections Services

Migration speed differences can often be detected for different glycan isoforms carried by the same protein.

Transferrin isoforms in cerebrospinal fluid and their relation to neurological diseases

Glycans play diverse roles in biotherapeutics, novel drug development, the study of bacterial physiology, and proteomics research.

Agilent Technologies Closes Acquisition of ProZyme, Expanding Biopharma Consumables Portfolio

"I see that PREMIER Biosoft's current range of software products have an extensive database and robust algorithms in place for released glycan analysis.

Dr. Jonathan Bones Joins PREMIER Biosoft Scientific Advisory Board to Further the Development of Glycomics Software Solutions for Biopharmaceutical Research & Development

She theorised broad-range glycan antibody assessments could one day become part of a routine patient exam, like blood levels of cholesterol and lipids, which provide early clues that something is amiss.

New tech helps in identifying biomarkers for diseases

Abnormal glycosylation is also known to be associated with a variety of diseases, such as cancer, inflammation, and neurotransmitter diseases.[6],[7] In 2016, Suzuki et al .[8] analyzed the glycan profile of urinary protein and showed that the expression of IgA1 was elevated in IgAN patients with galactose deficiency and that urinary Gd-IgA1 levels were associated with proteinuria.

Potential Value of Datura stramonium Agglutinin-recognized Glycopatterns in Urinary Protein on Differential Diagnosis of Diabetic Nephropathy and Nondiabetic Renal Disease

PNGase F-released glycans were purified by graphitized carbon cartridges (GlykoClean[TM] Glycan Clean-up Station, Vacuum Manifold, GC 100, Prozyme).

Combination of Microwave-Assisted Girard Derivatization with Ionic Liquid Matrix for Sensitive MALDI-TOF MS Analysis of Human Serum N-Glycans

The repertoire of human IgG Abs contains specificity not only for microbial antigens but also for a broad spectrum of host glycans that serve as attachment sites for viral and bacterial pathogens and/or exotoxins [14].

IgG Antibodies to GlcNAc[beta] and Asialo-GM2 (GA2) Glycans as Potential Markers of Liver Damage in Chronic Hepatitis C and the Efficacy of Antiviral Treatment

Inhibition of sialylation on N-glycosylation is made by removing the Asn 420 and 579-linked glycans which causes ligand-independent dimerization (25).

Cell Surface Sialylated N-Glycan Alterations during Development

Glycosylated proteins and their sugar moieties called glycans are key to a variety of important cellular processes, but they have historically been difficult to measure, owing in part to low plasma concentrations.

The Role of Emerging Biomarkers in Unraveling the Complex Biology Underlying Associations between HDL Cholesterol and Cardiovascular Diseases

The system is the ideal tool to analyze all major biopharmaceutical attributes, including aggregates, glycans, charge variants, peptide sequence and intact proteins.

Biocompatible analysis: Thermo Fisher Scientific Inc

The conference includes essential topics on Glycobiology, Glycans in Drug Design, Glyco Bioinformatics, Glyco Proteomics, Glyco Immunology, Glyco Biomarkers, Genomics and Metabolomics, Glycobiology and Biotechnology, Glycans in Diseases and Therapeutics, Glycans in Genetic Disorders, Structural Biology, Glycobiology in Personalized Medicine, Glycobiology in vaccine development and many more.