Pyrroloquinoline quinone against
glutamate-induced neurotoxicity in cultured neural stem and progenitor cells.
Guo et al., "Pyrroloquinoline quinone against
glutamate-induced neurotoxicity in cultured neural stem and progenitor cells," International Journal of Developmental Neuroscience, vol.
Glutamate-induced neurotoxicity may be caused by glutamate and NMDA receptors, which could produce oxidative damage, thus leading to apoptosis [24].
Persicarin from water dropwort ( Oenanthe javanica ) protects primary cultured rat cortical cells from
glutamate-induced neurotoxicity. Phytother Res 2010;24:913-8.
Several signaling pathways are involved in the regulation of
glutamate-induced neurotoxicity (14,15).
MeCbl also has neuronal protection including promoting injured nerve and axonal regeneration [9,10] and confronting against
glutamate-induced neurotoxicity [9,11].
Thus, the present study demonstrated the neuroprotective effect of insulin against
glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells that express insulin receptor by multiple mechanisms involving reduction in glutamate-induced cell loss, prevention of apoptosis, and reducing the production of reactive oxygen species.
Saitoh et al., "Attenuation by PACAP of
glutamate-induced neurotoxicity in cultured retinal neurons," Brain Research, vol.
These finding may explain the neuroprotective mechanism of minocycline in models of global and focal cerebral ischemia, the R6/2 model of Huntington's disease, as well as
glutamate-induced neurotoxicity in mixed neuronal/ glial cultures (9).
* Aripiprazole inhibits
glutamate-induced neurotoxicity and, in contrast to haloperidol, increases BDNF, glycogen synthase kinase (GSK)-1[beta], and the anti-apoptotic protein Bc1-2.
platyphylla bark and platyphylloside against
glutamate-induced neurotoxicity in HT22 hippocampal cells were evaluated (Table 1).
Attenuation of
glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM l.
