glucuronide

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glucuronide

 [gloo-ku´ron-īd]
any glycosidic compound of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols, and carboxylic acids.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

glu·cu·ro·nide

(glū-kū'rōn-īd),
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (for example, steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.
Synonym(s): glucuronoside
Farlex Partner Medical Dictionary © Farlex 2012

glu·cu·ro·nide

(glū-kyūr'ō-nīd)
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (e.g., steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Simultaneous determination of mycophenolic acid and its glucuronide in human plasma using a simple high-performance liquid chromatography procedure.
Hydrolysis of steroid glucuronides with [beta]-glucuronidase preparations from bovine liver, Helix pomatia, and E.
Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs.
The stability of the glucuronides of some steroids in dried blood spots stored for 1 week at room temperature, compared with aliquots maintained in a freezer (-20 [degrees]C), was verified (Fig.
We recently characterized two further metabolites of MPA, including an acyl glucuronide metabolite (AcMPAG), in the plasma of liver, kidney, and heart transplant recipients receiving MMF (4).
Biosynthesis of these steroid molecules in human beings is constant, and in the urine the normal testosterone glucuronide and epitestosterone glucuronide ratio (T/E) ranges between 0.4 and 2 (bimodal variation is in line with genetic polymorphism).
Schematic overview of the PBPK model for BPA, BPS, BPF, and BPAF and their glucuronides and sulfates (PBPK-compartments in gray, single-compartment submodules with dotted lines).
Future investigations are required to clarify the mechanism allowing kidney extracts to convert bile acids into acyl glucuronides in the absence of the UGT1A3 protein.
Our results showed that compounds 6 and 10, which contain a glucuronide at position 7 in the A ring and di-hydroxyl groups in the B ring of the flavonol skeleton, exhibited the highest AGE inhibitory activity.
Since the glucuronides of morphine and other opiates have been