glucose-dependent insulinotropic peptide


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Related to glucose-dependent insulinotropic peptide: gastric inhibitory polypeptide

glucose-dependent insulinotropic peptide

A hormone released by cells in the upper gastrointestinal tract in response to sugary or fatty meals. It stimulates beta cells in the pancreas to secrete insulin.
See also: peptide
References in periodicals archive ?
Alogliptin, discovered by Takeda San Diego, is intended to slow the inactivation of incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide), which participate in the regulation of blood glucose levels.
The DPP-IV inhibitors work by blocking the enzyme that breaks down the two incretin hormones glucagonlike peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide, which help regulate glucose metabolism via increased insulin release, suppressed glucagon release, and delayed gastric emptying.
This phenomenon is called the incretin effect and is due to the secretion of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) which increases the glucose-induced insulin secretion [3].

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