glucose intolerance


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Related to glucose intolerance: Gluten intolerance, Impaired glucose tolerance

intolerance

 [in-tol´er-ans]
inability to withstand or consume; inability to absorb or metabolize nutrients.
activity intolerance a nursing diagnosis accepted by the North American Nursing Diagnosis Association, defined as a state in which a person has insufficient physiological or psychological energy to endure or complete necessary or desired daily activities. Causes include generalized weakness, sedentary lifestyle, imbalance between oxygen supply and demand, and bed rest or immobility. Defining characteristics include verbal report of fatigue or weakness, abnormal heart rate or blood pressure response to activity, exertional discomfort, and dyspnea.
carbohydrate intolerance inability to properly metabolize one or more carbohydrate(s), such as glucose, fructose, or one of the disaccharides.
disaccharide intolerance inability to properly metabolize one or more disaccharide(s), usually due to deficiency of the corresponding disaccharidase(s), although it may have other causes such as impaired absorption. After ingestion of the disaccharide there may be abdominal symptoms such as diarrhea, flatulence, borborygmus, distention, and pain. One common type is lactose intolerance.
drug intolerance the state of reacting to the normal pharmacologic doses of a drug with the symptoms of overdosage.
exercise intolerance limitation of ability to perform work or exercise at normally accepted levels, as measured in exercise testing.
glucose intolerance inability to properly metabolize glucose, a type of carbohydrate intolerance; see diabetes mellitus.
lactose intolerance a disaccharide intolerance specific for lactose, usually due to an inherited deficiency of lactase activity in the intestinal mucosa.
risk for activity intolerance a nursing diagnosis accepted by the North American Nursing Diagnosis Association, defined as the state in which an individual is at risk of having insufficient physiological or psychological energy to endure or complete required daily activities. See also activity intolerance.
Patient Care. Nursing activities and interventions are aimed at identifying those factors that contribute to activity intolerance, providing evidence of the patient's progress to the higher level of activity possible for the patient, and reducing signs of physiologic intolerance to increased activity (blood pressure and respiratory and pulse rates). Once the contributing factors are identified, plans are made to avoid or minimize them. For example, if inadequate sleep or rest periods are a factor, the nurse plans with the patient scheduled periods of uninterrupted rest during the day. Inadequate sleep at night should be assessed and appropriate interventions planned and implemented. Making an objective record of the patient's progress toward increased activity tolerance can help alleviate depression or lack of incentive, both of which can be contributing factors. Such assessment data could include measurements of blood pressure, pulse, and respiratory rates before and after an activity, gradual increase in the distance walked, and gradual resumption of responsibility for activities of daily living.

glu·cose in·tol·er·ance

(glūkōs in-tolĕr-ăns)
Sometimes called "prediabetes," usually diagnosed by measuring fasting blood sugar levels.
References in periodicals archive ?
Benhalima, "Glucose intolerance in early postpartum in women with gestational diabetes: who is at increased risk?," Primary Care Diabetes, vol.
GC in excess exerts diabetogenic actions that include the increase in plasma triacylglycerol and NEFA levels and the reduction in peripheral insulin sensitivity [2-5, 16, 17], accompanied by an increase in blood glucose levels and the presence of glucose intolerance [2-7,16, 17].
Since artificial sweeteners are largely undigested and come into direct contact with gut microbes, the researchers decided to test whether a change in the microbiota accounted for the development of glucose intolerance. They fed two groups of mice normal chow and gave them water with commercial saccharin or water with glucose to drink.
It is known that diet-induced obesity, in mice, also provokes glucose intolerance accompanied by increased insulin secretion, which compensates for the peripheral insulin resistance [17].
* Diagnosis of diabetes mellitus and glucose intolerance were made by WHO criteria.
Gestational diabetes mellitus is a degree of glucose intolerance with onset or first recognition amid pregnancy.6 Similar to different individuals from the Asian race, Pakistani women are likewise thought to be at a high hazard for developing gestational diabetes.7 A number of maternal risk factors have been identified for development of GDM.
Thus, the influence of aerobic physical exercise and metformin on development of acute glucose intolerance in rats was evaluated.
The first study, published in Nature by a team of Israeli medical researchers, found that mice fed water spiked with one of three common fake sweeteners (saccharin, aspartame, and sucralose) had a much higher tendency than the control group to develop glucose intolerance, a precursor to diabetes.
(However, the mice fed aspartame appeared to have little or no glucose intolerance, and saccharin and sucralose affected only some "responders.")
Glucose intolerance -- generally thought to occur when the body cannot cope with large amounts of sugar in the diet -- is the first step on the path to metabolic syndrome and adult-onset diabetes.
Some of these include being overweight or obese; problems with glucose and/or insulin, such as glucose intolerance and insulin resistance; and type 2 diabetes.
Studies in adults have linked type 2 diabetes risks and experimental sleep restriction to acute insulin resistance and glucose intolerance.