The aim of the research was not only the production of a non-enzyme biosensor to detect glucose, but also to eliminate the expensive nafion and glucose oxidase enzyme
in the design and production of the sensor.
The glucose oxidase enzyme
interacts with the glucose and any free oxygen in the formulation, generating hydrogen peroxide.
The Precision G and the Precision QID glucose meters have a third background compensation electrode that lacks glucose oxidase enzyme
and measures the signal from potentially interfering substances.
The latest blood glucose meters use a coulometric technique where a capillary action on the test strip takes in the blood sample that is fed to an electrode containing glucose oxidase enzyme
. After reoxidizing the enzyme with ferrocyanide ions, the total charge passing through the electrode yields the glucose concentration in the blood.
The new, injectable nano-network is composed of a mixture that contains nanoparticles with a solid core of insulin, modified dextran and glucose oxidase enzymes