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Related to Glucoraphanin: Sulforaphane


An isothiocyanate phytochemical present—after conversion from glucoraphanin by myroinase—in cruciferous vegetables (e.g., Brussels sprouts, broccoli, cabbage), which has anticarcinogenic, antimicrobial and antidiabetic activity in experimental systems. 
It stimulates the production of phase-2 enzymes that play a role in detoxifying carcinogens; in rats, sulphoraphane reduces the incidence of mammary tumours induced by dimethylbenzanthracene (DMBA).


Sulforaphane glucosinolate, sulphoraphane Oncology An isothiocyanate phytochemical or 'nutriceutical' in cruciferous vegetables–eg, broccoli, which may prevent CA. See Cruciferous vegetables, Nutriceutical.


, sulphoraphane (sŭl-fŏr′ă-fān″) [″ + Gr. phainein, to show],


A sulfur-containing compound found in vegetables of the mustard family (Cruciferae). Like other isothiocyanates, it has been shown to prevent cancer in animals.
References in periodicals archive ?
The effect of sulfur fertilizer on glucoraphanin levels in broccoli (B.
In the early 1990's, scientists identified glucoraphanin, the naturally occurring compound in broccoli which converts to the antioxidant sulforaphane by enzymes in broccoli (myrosinase) or gut microflora in the body.
In 1997 it was discovered that 3-4 day old broccoli sprouts were the holders of up to 20 times the concentration of glucoraphanin when compared to the adult plant.
The ideal sulforaphane-releasing supplement retains both its glucoraphanin precursor and its myrosinase enzyme in the form of a whole broccoli sprout ingredient with nothing but water removed.
Not all foods contain the same amount of glucoraphanin.
Glucoraphanin works by breaking fat down in the body, preventing it from clogging the arteries.
Of particular interest is its glucoraphanin content.
Research suggests the plant chemical, glucoraphanin, may protect the body against heart disease and some types of cancer.
Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.
For anti-ageing, BroccoRaphanin, one of Frutarom's SelectLine, is a broccoli concentrate containing standardized glucoraphanin.
Researchers at the ARS Vegetable Research Unit in Charleston, SC and at Johns Hopkins University in MD have bred broccoli with 30 times the supposed anti-cancer phytochemical glucoraphanin.