GRIA3

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GRIA3

A gene on chromosome Xq25 that encodes a member of the excitatory neurotransmitter glutamate receptor family, which are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) and function as ligand-activated cation channels.
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References in periodicals archive ?
Caption: Figure 6: Immunohistochemistry results showing the expression of GluA3 in the subregion of the hippocampus.
We have characterized the distribution of the GluA3 and Glu-B3 loci alleles in the mini core collections of Chinese wheat germplasms [25].
It is composed of four subunits: GluA1, GluA2, GluA3, and GluA4, which form a heterotetramer.
GluA2, GluA3, and possibly GluA4 subunits of AMPAR are present in SGN afferent dendrites in the adult cochlea [38], and the GluA2 subunit determines the key biophysical properties of GluAs in vivo [39].
These receptors are composed of four types of subunits: GluA1, GluA2, GluA3 and GluA4 [141].
GluA1 or GluA1/A2 are regulated by P2X activation while GluA3 homomers are insensitive and their presence in heteromers alters P2X-mediated inhibition.