focal segmental glomerulosclerosis(redirected from Glomerulosclerosis, focal)
diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.
focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
fo·cal seg·men·tal glo·mer·u·lo·scle·ro·sis
segmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix; seen in some glomeruli of patients with nephrotic syndrome or mesangial proliferative glomerulonephritis.
Farlex Partner Medical Dictionary © Farlex 2012
fo·cal seg·men·tal glo·mer·u·lo·scle·ro·sis(fō'kăl seg-men'tăl glo-mer'yū-lō-skler-ō'sis)
Segmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix; seen in some glomeruli of patients with nephrotic syndrome or mesangial proliferative glomerulonephritis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
focal segmental glomerulosclerosis
An irreversible form of glomerular injury often seen in patients with a history of injection drug use or acquired immunodeficiency syndrome.
See also: glomerulosclerosis
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