gliquidone


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gliquidone

A SULPHONYLUREA drug used to treat maturity onset (Type II) DIABETES. A brand name is Glurenorm.
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Schneider, Rapid extraction, identification and quantification of oral hypoglycaemic drugs (glipizide, glibenclamide, gliclazide, gliquidone and metformin) in serum and hair using LC- MS/MS, Forensic Sci.
A pharmacokinetic study on Huangqi injection combined with other drugs such as gliquidone has also provided further reference and basis for the clinical use of Huangqi injection [61].
Zhou et al., "Pharmacokinetics and hepatic uptake of gliquidone affected by Huangqi injection," European Journal of Drug Metabolism and Pharmacokinetics, vol.
Developed by Boehringer-Ingelheim, gliquidone first came into the German market in 1975 under the trade name of Glurenorm.
As gliquidone is expelled from the body with bile after being metabolized by CYP3A4 enzyme system in the liver and only 6% of it is excreted through kidney, it is more suitable for patients with kidney disorders.
And glibenclamide, gliquidone, gliclazide and glimepiride are the common drugs in the class of sulfonylurea.
And glibenclamide, gliquidone, glipizide and glimepiride are the common drugs in the class of sulfonylurea.
Group III mice, i.e., the positive control mice, were administered 100 mg kg body [weight.sub.-1] of gliquidone in 0.86% NaCl.
STZ and gliquidone were purchased from Sigma Chemical Co., USA and Beijing Wanhui Double-Crane Pharmaceutical Co., China, respectively.
Category Name CID Tolbutamide 5505 Glyburide 3488 Glipizide 3478 Sulfonylureas drug Gliquidone 91610 Glimepiride 3476 Gliclazide 3475 Metformin 4091 Phenformin 8249 Biguanide drug Acarbose 441184 Voglibose 444020 Miglitol 441314 Euglycemic agent Pioglitazone 4829 Rosiglitazone 77999 Euglycemic agent Repaglinide 65981 (Nonsulfonylurea) Starsis (TN) 443871 Aldose reductase inhibitor Tolrestat 53359 Alrestatin 2120 Table 2: Potential antidiabetic ingredients in Ge-Gen-Qin-Lian formula by network target analysis.
Siddiqui, "Simultaneous determination of gliquidone, fexofenadine, buclizine, and levocetirizine in dosage formulation and human serum by RP-HPLC," Journal of Chromatographic Science, vol.