Gleason score

(redirected from Gleason system)

Glea·son tu·mor grade

(glē'sŏn),
a classification of adenocarcinoma of the prostate by evaluation of the pattern of glandular differentiation; the tumor grade, known as Gleason score, is the sum of the dominant and secondary patterns, each numbered on a scale of 1 to 5.
Farlex Partner Medical Dictionary © Farlex 2012

Gleason score

Oncology A value derived from the Gleason grading system which is the sum of the 2 most predominant histologic patterns seen in prostate CA.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Gleason score

A method of grading malignancy of prostate cancers, based on the pattern of glandular differentiation. Both the dominant and secondary patterns of differentiation are scored on a scale of 1 to 5, and the Gleason score, is the sum of the two scores.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Gleason,

Donald F., U.S. pathologist, 1920–.
Gleason score
Gleason tumor grade - a classification of adenocarcinoma of the prostate.
Medical Eponyms © Farlex 2012
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References in periodicals archive ?
Gleason's work was validated by most of the preeminent urologic pathology groups, (6-10) and the Gleason system became accepted as the preferred grading method for PCa.
Moving Beyond Gleason Scoring
Due to this diversity, the final grade as reported by the Gleason system is based on the combination of the most dominant and second most dominant patterns observed.
Artificial intelligence at the intersection of pathology and radiology in prostate cancer
There are some problems with the clinical application of the Gleason system. Notification of the significant prognostic difference between prostate carcinomas with Gleason grade 3+4 and 4+3 revealed that treatment decisions using a single Gleason score misdirect the management of patients.
Current Status of Histologic Grading in Prostate Carcinoma and Renal Cell Carcinoma / Prostat Karsinomu ve Renal Hucreli Karsinoma Histolojik Derecelemesinde Son Durum
After examining the haematoxylin and eosin stained slides, the tumours were classified according to modified Gleason system with ISUP recommendations.
Diagnostic utility of AMACR in prostatic carcinoma
The histopathological grading and scoring by Gleason system was carried out in all cases of adenocarcinoma of prostate, criteria for the grading and scoring of needle biopsies of the prostate.
Correlation of serum prostate-specific antigen level in various prostate pathology in elderly men
All patients with prostate cancer were scored according to Gleason system.
Expression of Telomere Repeat Binding Factor 1 and TRF2 in Prostate Cancer and Correlation with Clinical Parameters
(5,6) Moreover, the differences between the original Gleason system and the 2005 ISUP Modified Gleason System make it difficult to compare data sets assessing patient outcomes in prostate cancer over time.
Salvage radiation therapy 11 years after a radical prostatectomy
The Gleason system uses a score of two to 10 to analyze a tumor; a score between eight and 10 suggests an aggressive, fast-growing tumor that's probably spread beyond the prostate gland.
Seeds of hope Sarasota's Dattoli Institute's innovative prostate cancer treatment gives Randy Drymiller a new lease on life
At McCaffrey's, a three-store New Jersey independent that has had the system for six years, managers use the Gleason system for hourly store walk-throughs.
An ounce of prevention: accidents are a liability, but the right gear and training can cut the risks
The most critical threshold in the Gleason system is in the recognition of patterns 4 and 5.
The challenges of prostate cancer detection
There have been continued efforts in improving the Gleason system for risk stratification.
Prostate Cancers Detected by Magnetic Resonance Imaging-Targeted Biopsies Have a Higher Percentage of Gleason Pattern 4 Component and Are Less Likely to Be Upgraded in Radical Prostatectomies
We estimated tumour grade after the contemporary criteria of 2005 ISUP modified Gleason system.[sup.9]
The role of PSA density to predict a pathological tumour upgrade between needle biopsy and radical prostatectomy for low risk clinical prostate cancer in the modified Gleason system era

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